Golimumab (Simponi Aria®) is a human IgG1κ monoclonal antibody specific for human tumor necrosis factor alpha (TNFα), a cytokine protein. Golimumab is an antibody with human-derived antibody variable and constant regions. Golimumab binds to both soluble and transmembrane bioactive forms of TNFα, blocking the binding of TNFα to its receptors and inhibiting the biologic activity of TNFα.
Patient Medication Guide
Full Prescribing Information
Golimumab is indicated for adults with moderately to severely active rheumatoid arthritis in combination with methotrexate
Rheumatoid Arthritis (RA)
Specific contraindications have not been determined.
Most common adverse reactions (>3%):
If the answer is yes to any of these questions, notify the ordering provider before initiating the infusion therapy.
Updated January 2017 - ARP Practice Committee
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