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Golimumab (Simponi Aria®) is a human IgG1κ monoclonal antibody specific for human tumor necrosis factor alpha (TNFα), a cytokine protein. Golimumab is an antibody with human-derived antibody variable and constant regions. Golimumab binds to both soluble and transmembrane bioactive forms of TNFα, blocking the binding of TNFα to its receptors and inhibiting the biologic activity of TNFα.
Patient Medication Guide
Full Prescribing Information
Golimumab is indicated for adults with moderately to severely active rheumatoid arthritis in combination with methotrexate
Rheumatoid Arthritis (RA)
Specific contraindications have not been determined.
Most common adverse reactions (>3%):
If the answer is yes to any of these questions, notify the ordering provider before initiating the infusion therapy.
Updated January 2017 - ARP Practice Committee
DISCLAIMER:The information contained in this biologic reference guide is offered solely for purposes of providing health care professionals with a quick and initial reference. Before prescribing or administering any drug contained in this biologic reference guide, health professionals should read the manufacturer’s complete prescribing information in order to be informed of the various clinical considerations to be taken into account. The American College of Rheumatology is providing this information as a benefit and service in furtherance of its educational mission. By providing this information, ACR is not endorsing or recommending any of the listed companies or any of their drugs or other products. The information contained in the biologic reference guides reflect the conclusions of the individual companies and not those of the ACR which specifically disclaims any responsibility or liability for the use of such information and/or for the performance of any of the drugs listed in this biologic reference guide.