Looking for rheumatic disease types, treatments, and associated rheumatology definitions? From abatacept to WOMAC, learn about common terms related to arthritis and rheumatic and musculoskeletal diseases. Looking for information about MACRA? See MACRA terms and definitions.

Human leukocyte antigen (HLA)

System designation for the gene products of at least four linked loci and a number of subloci on the sixth human chromosome that have been shown to have a strong influence on human allotransplantation.

Hyaluronic acid

Mucopolysaccharide made up of alternating b1,4-linked residues of hylabiuronic acid, forming a gelatinous material in the tissue spaces and acting as a lubricant and shock absorbant generally throughout the body; belongs to disease-modifying antirheumatic drug class of drugs.

Hydroxychloroquine (Plaquenil)

Oral medicine used in the treatment of arthritis to help relieve inflammation, swelling, stiffness, and joint pain and to help control the symptoms of lupus erythematosus (lupus).

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High blood pressure.


Enhanced blood concentrations of uric acid.


Abnormally low levels of calcium in the circulating blood; commonly denotes subnormal concentrations of calcium ions.


Decreased below normal levels of oxygen in inspired gases, arterial blood, or tissue, short of anoxia.

Ibandronate (Boniva)

Oral and intravenous drug that is used for treating osteoporosis. It is a member of the bisphosphonate class of drugs. After menopause, there is an increased rate of bone loss leading to osteoporosis, and ibandronate has been shown to increase bone density and decrease fractures of bones.

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Production of a clinical image using x-rays, ultrasound, computed tomography, magnetic resonance imaging, radionuclide scanning, and thermography.


State or property of being antigenic.

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