Looking for rheumatic disease types, treatments, and associated rheumatology definitions? From abatacept to WOMAC, learn about common terms related to arthritis and rheumatic and musculoskeletal diseases. Looking for information about MACRA? See MACRA terms and definitions.

Fracture Risk Assessment Tool (FRAX)

Developed by World Health Organization to evaluate fracture risk of patients. Based on individual patient models that integrate the risks associated with clinical risk factors as well as bone mineral density at the femoral neck. The algorithms give the 10-year probability of fracture. The output is a 10-year probability of hip fracture and the 10-year probability of a major osteoporotic fracture (clinical spine, forearm, hip, or shoulder fracture).

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A break, especially the breaking of a bone or cartilage.


Manner of walking.


Relating to the stomach and intestines.


Category to which an individual is assigned by self or others, on the basis of sex.

Gene expression

Detectable effect of a gene; appearance of an inherited trait.

Gene therapy

Alteration of somatic or germ-line DNA to correct or prevent diseases; the process of inserting a gene artificially into the genome of an organism to correct a genetic defect or to add a new biologic property or function with therapeutic protocol.


Branch of science concerned with the means and consequences of transmission and generation of the components of biologic inheritance.


Study of the structure of the genome of particular organisms, including mapping and sequencing.


Branch of medicine concerned with the medical problems and care of the aged.

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