Glossary

Looking for rheumatic disease types, treatments, and associated rheumatology definitions? From abatacept to WOMAC, learn about common terms related to arthritis and rheumatic and musculoskeletal diseases. Looking for information about MACRA? See MACRA terms and definitions.

Epidemiology

Study of the distribution and determinants of health-related states or events in specified populations, and application of this study to control of health problems.

Erosions

Shallow ulcer; in the stomach and intestine, an ulcer limited to the mucosa, with no penetration of the muscularis mucosa.

Erythrocyte sedimentation rate (ESR)

Rate of settling of red blood cells in anticoagulated blood.

Etanercept (Enbrel)

A dimeric fusion protein consisting of the extracellular ligand-binding portion of the tumor necrosis factor (TNF) receptor linked to the Fc portion of human IgG1. Used in the treatment of inflammatory disorders such as Crohn’s disease and rheumatoid arthritis.

Ethics

Branch of philosophy that deals with the distinction between right and wrong, with the moral consequences of human actions.

Exercise

Bodily exertion for the sake of restoring the organs and functions to a healthy state or keeping them healthy.

Familial Mediterranean fever

Inheritable disease caused by a gene mutation. Causes inflammation of the joints, lungs, or abdomen, as well as recurring fevers. Other symptoms include chest pain, muscle aches, rashes, swollen scrotum in men, constipation, and diarrhea. Typically occurs in ethnic groups with ancestry in the Mediterranean Sea region, such as Arabs, Armenians, Italians, Sephardi Jews, and Turks. Usually is diagnosed in childhood. Colchicine may help control inflammation.

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Fatigue

State, followed by a period of mental or reduced bodily activity, characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness, sleepiness, or irritability; may also supervene when, from any cause, energy expenditure outstrips restorative processes and may be confined to a single organ.

Fc receptor

Present on a variety of cells for the Fc fragment of immunoglobulins; recognizes immunoglobulins of the IgG and IgE class.

Fibromyalgia (FM)

Syndrome of chronic pain of musculoskeletal origin but uncertain cause. Is accompanied by fatigue, sleep, memory, and mood issues.

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