Raynaud’s Phenomenon

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Fast Facts

  • Raynaud’s Phenomenon can be classified as either primary or secondary
  • Approximately 10% of the population has Primary Raynaud’s
  • Treatment depends on the severity of the Raynaud’s and whether it is associated with another condition
  • Typically, Raynaud’s is not disabling but can affect quality of life

Raynaud’s Phenomenon is a process in which the fingers (and less commonly, the toes) turn different colors (white, blue, and red) in response to certain triggers such as cold or stress. It can be associated with discomfort or a “pins and needles” sensation. It is due to the small blood vessels in the fingers that “spasm”, thus decreasing blood flow to the fingertips. Individuals should seek the care of a rheumatologist if they have frequent or severe symptoms, or if they develop sores on their fingertips.

What Is Raynaud’s Phenomenon (RP)?

Raynaud’s Phenomenon (RP) results when there is a decrease in blood flow to the fingers and toes when someone is exposed to cold weather or stress. Symptoms can occur due to cold exposure such as reaching into a freezer or being near an air conditioner. The fingers or toes typically change colors including white, blue and red. This can be associated with a “pins and needles” sensation (numbness) or discomfort. These symptoms occur intermittently, and are known as “episodes” or “attacks”, and tend to resolve on their own.

It is important to know there are two types of Raynaud’s Phenomenon – these are referred to as “primary” and “secondary”. Primary Raynaud’s typically affects women typically under the age of 30 (usually in the teenage years or early twenties). While symptoms can be uncomfortable, there is no danger of damage to the body. Primary Raynaud’s occurs in patients who do not have another rheumatic disease. Secondary Raynaud’s is “secondary” to another condition. These conditions are numerous and can include several autoimmune conditions. The most common rheumatic diseases associated with Raynaud’s include scleroderma and lupus, but can include others such as rheumatoid arthritis, myositis, thyroid dysfunction, and Sjögren’s syndrome. Often, the onset of secondary RP is later in life – usually after the age of 30.

What Causes Raynaud’s Phenomenon?

Raynaud’s phenomenon is caused by overly-sensitive blood vessels within the fingers and toes. They are more affected by cold and stress. The blood vessels narrow substantially, causing a decrease in blood flow and associated color change. The lack of blood flow often results in a pale, or white, discoloration. Subsequently, the digits can turn blue and eventually red as there is a sudden influx of blood into the digits after the episode is over.

How Is Raynaud’s Phenomenon Diagnosed?

RP is diagnosed based on a history and physical examination. Patients with primary Raynaud’s typically have a normal examination and blood work. Patients with secondary Raynaud’s typically have an abnormal exam and/or blood work. An exam technique that involves looking at the blood vessels below the fingernails (called nailfold capillaroscopy) can also be performed.

How Is Raynaud’s Phenomenon Treated?

Raynaud’s can be managed with both lifestyle modifications and medications.

Lifestyle modifications include keeping the body warm, specifically, keeping the core of the body warm. Often times patients will use hand warmers and mittens/gloves to help keep the fingers warm. Stress reduction and smoking cessation are also recommended to help decrease Raynaud’s attacks.

Many patients can control their symptoms with lifestyle modification alone. However, sometimes medications are needed, and many options are available. These include blood pressure medications such as calcium channel blockers (amlodipine, nifedipine, felodipine, and others) and angiotensin-receptor blockers. These medications act by increasing blood flow to the fingers and toes. For patients with more severe symptoms or who have developed complications such as ulcers on the fingertips, other medications can be used including sildenafil or prostacyclins.

Sometimes, patients will also be prescribed other medications that can help improve symptoms, including topical creams, selective-serotonin-reuptake inhibitors (SSRIs), or cholesterol-lowering (statin) medications.

The Rheumatologist's Role in the Treatment of Raynaud’s Phenomenon

RP is often diagnosed by a rheumatologist, who further can decide whether the Raynaud’s is primary or secondary. Rheumatologists are doctors who are experts in diagnosing and treating arthritis and other diseases of the joints, muscles and bones. Thus, they are best qualified to make a proper diagnosis of Raynaud’s Phenomenon. They can also advise patients about the best treatment options.

Updated December 2021 by the American College of Rheumatology Committee on Communications and Marketing.

This information is provided for general education only. Individuals should consult a qualified health care provider for professional medical advice, diagnosis and treatment of a medical or health condition.

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