Watch ViTLs Adult Playlist
Mimics: Scleroderma / Vasculitis / Spondyloarthropathy
Marcy Bolster, MD
Laura Hummers, MD, MS
Matthew Koster, MD
David Borenstein, MD, MACR, MACP
In this session, Laura Hummers, MD, MS, uses a case-based format to review the differential diagnosis of thickened skin, highlighting key clinical ways to differentiate scleroderma from scleroderma mimics. In their case-based presentations, Matthew J. Koster, MD, discusses three vasculitis mimics and provides guidance on how to effectively use details in the history, exam, imaging and ancillary studies to successfully differentiate between these mimics and true vasculitis. David Borenstein, MD, MACR, MACP, discusses the characteristic changes noted in the lumbar spine and sacroiliac joints that differentiate ankylosing spondylitis from other spinal disorders that cause abnormal calcification of these structures.
Learning Objectives
- Compare and contrast the clinical features of scleroderma and its mimics
- Overview salient points about the mimics of scleroderma
- Briefly discuss treatment strategies for scleroderma mimics
- Discuss three vasculitis mimics
- Recognize features that differentiate vasculitis mimics from true disease
- Review of the normal structures of the lumbar spine observed with plain radiographs, the modifications of the intervertebral disks in spinal disorders
- Review observations needed to determine if multiple disorders are present in a single individual
Macrophage Activation Syndrome / HLH
Tyler Reese, MD
McKenzie Rose Vater, MD
Alexei Grom, MD
Michelle Hermiston, MD, PhD
In the presentation, Macrophage Activation Syndrome – Early Recognition and Therapeutic Targets, Alexei Grom, MD, discusses initial diagnostic evaluation, pathophysiology and emerging therapeutic targets in macrophage activation syndrome. In the presentation, Diagnostic and Therapeutic Approach to HLH/MAS, Michelle Hermiston, MD, PhD, uses a case-based approach to discuss a systematic approach to the evaluation and management of a patient with suspected macrophage activation syndrome (MAS)/hemophagocytic lymphohistiocytosis (HLH).
Learning Objectives
- Recognize clinical patterns that should trigger full evaluation for MAS
- Discuss the current MAS diagnostic criteria
- Discuss current treatment approaches and emerging new therapeutic targets
- Identify HLH as a clinical syndrome that can be caused by multiple etiologies
- Explain the pathophysiology of HLH and its common manifestations
- Describe treatment modalities for newly diagnosed and refractory patients
EGPA
Anish Dua, MD, MPH
Philip Seo, MD, MHS
Mike Wechsler, MD, MMSc
Fei Li Kuang, MD, MPH
Mike Wechsler, MD, MMSc, focuses on the functions and roles of eosinophils and the treatment strategies for hypereosinophilic conditions.Fei Li Kuang, MD, PhD, highlights and discusses the similarities and differences in the diagnoses of EGPA and HES, and why that matters, especially in an era where targeted anti-eosinophil therapies are available.
Learning Objectives
- Describe differing definitions of hypereosinophilic syndromes (HES) and how that could overlap with EGPA
- Explain how differences in diagnosis impacts treatment and outcomes
- Discuss role of directed anti-eosinophil therapy in EGPA
- Describe multiple functions of eosinophils
- Review differential diagnosis of eosinophilic lung diseases
- Discuss novel treatment strategies for hypereosinophilic conditions
Psoriatic Arthritis
Lianne Gensler, MD
Elaine Husni, MD, MPH
Gurjit Kaely, MBBS, MRCP
In this session, Elaine Husni, MD, MPH, reviews the clinical presentation, management strategies, and treatment options for psoriatic arthritis, as well as an emphasis on how the disease affects the patient. In addition, Gurjit Kaeley, MRCP, RhMSUS, reviews the clinical utility and sonographic features of psoriatic arthritis, including the domains of enthesitis, dactylitis, and psoriatic joint disease.
Learning Objectives
- Recognize the various clinical presentation and the delay in diagnosis that can occur in patients with psoriatic arthritis (PsA)
- Describe the best practices around management strategies for PsA and identify approved and emerging therapeutic options
- Describe the utility of sonography in the evaluation of PsA
- Recall the sonographic features of enthesitis, psoriatic joint disease, and dactylitis
Sarcoidosis
Nadera Sweiss, MD
Prashant Parmar, MD
Omar F. Abou-Ezzeddine, MD, CM, MS
Pooja Bhat, MD
Nadera Sweiss, MD, and Prashant Parmar, MD, provide an overview of the management and treatment of sarcoidosis. The session also includes presentations on both sarcoid heart disease and ocular sarcoidosis by Omar F. Abou-Ezzeddine, MD, CM, MS, and Pooja Bhat, MD, respectively.
Learning Objectives
- Recognize the challenges of the management of sarcoidosis
- Recognize the recent updates regarding sarcoidosis treatment
- Identify potential vision threatening complications of ocular sarcoidosis
- Understand aims of systemic immunosuppression in patients with non-infectious ocular inflammation
- Provide an overview of the pathophysiology and clinical presentation of sarcoid myocarditis
- Review diagnostic algorithms and the role of advanced imaging in the current era
- Offer a therapeutic approach for the management of sarcoid myocarditis