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Arthritis & Rheumatism
Official Journal of the American College of Rheumatology
Volume 48, No. 9, September 2003
Special
Articles |
| 2393
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Editorial:
The Exercise Prescription in Rheumatoid Arthritis: Primum non Nocere
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Axel
Finckh, Maura Iversen, and Matthew H. Liang |
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| 2396
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Editorial:
Interferon-[ga]: A New Target for Therapy in Systemic Lupus Erythematosus?
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Mary
K. Crow |
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| 2402
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Editorial:
Widespread Pain in Children: When Is It Pathologic? |
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Laura
E. Schanberg |
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| 2406
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Review:
Large-Vessel Vasculitis: Unresolved Issues |
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Gary
S. Hoffman |
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| Rheumatoid
Arthritis |
| 2415
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Is
a Long-Term High-Intensity Exercise Program Effective and Safe in Patients
With Rheumatoid Arthritis? Results of a Randomized Controlled Trial
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Zuzana
de Jong, Marten Munneke, Aeilko H. Zwinderman, Herman M. Kroon, Annemarie
Jansen, Karel H. Ronday, Dirkjan van Schaardenburg, Ben A. C. Dijkmans,
Cornelia H. M. Van den Ende, Ferdinand C. Breedveld, Theodora P. M.
Vliet Vlieland, and Johanna M. W. Hazes |
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| 2425
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Association
of Mortality With Disease Severity in Rheumatoid Arthritis, Independent
of Comorbidity |
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Gregorio
Navarro-Cano, Inmaculada del Rincon, Samvel Pogosian, Jose F. Roldan,
and Agustin Escalante |
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| 2434
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Doppler
Ultrasound and Magnetic Resonance Imaging of Synovial Inflammation of
the Hand in Rheumatoid Arthritis: A Comparative Study |
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L.
Terslev, S. Torp-Pedersen, A. Savnik, P. von der Recke, E. Qvistgaard,
B. Danneskiold-Sams\oe, and H. Bliddal |
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| 2442
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Activin
A Induces Cell Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid
Arthritis |
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Fumie
Ota, Akito Maeshima, Shin Yamashita, Hidekazu Ikeuchi, Yoriaki Kaneko,
Takashi Kuroiwa, Keiju Hiromura, Kazue Ueki, Itaru Kojima, and Yoshihisa
Nojima |
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| 2450
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Expression
of the MAPK Kinases MKK-4 and MKK-7 in Rheumatoid Arthritis and Their
Role as Key Regulators of JNK |
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Monisha
Sundarrajan, David L. Boyle, Martine Chabaud-Riou, Deepa Hammaker, and
Gary S. Firestein |
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| 2461
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Tie2
Receptor Tyrosine Kinase, a Major Mediator of Tumor Necrosis Factor
[ga]-Induced Angiogenesis in Rheumatoid Arthritis |
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Laura
M. DeBusk, Ying Chen, Toshihide Nishishita, Jin Chen, James W. Thomas,
and Pengnain Charles Lin |
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| 2472
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Rheumatoid
Fibroblast-Like Synoviocytes Overexpress the Chemokine Stromal Cell-Derived
Factor 1 (CXCL12), Which Supports Distinct Patterns and Rates of CD4+
and CD8+ T Cell Migration Within Synovial Tissue |
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Paul
F. Bradfield, Nicole Amft, Elizabeth Vernon-Wilson, Andrew E. Exley,
Greg Parsonage, G. Ed Rainger, Gerard B. Nash, Andrew M. C. Thomas,
David L. Simmons, Mike Salmon, and Christopher D. Buckley |
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| 2483
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Simultaneous,
Clonally Identical T Cell Expansion in Tonsil and Synovium in a Patient
With Rheumatoid Arthritis and Chronic Tonsillitis |
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Mitsuhiro
Kawano, Kanae Okada, Hiroaki Muramoto, Hajime Morishita, Takayo Omura,
Ryo Inoue, Susumu Kitajima, Kenichi Katano, Ichiro Koni, Hiroshi Mabuchi,
and Akihiro Yachie |
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| 2489
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Citrullination
of Synovial Proteins in Murine Models of Rheumatoid Arthritis
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Erik
R. Vossenaar, Suzanne Nijenhuis, Monique M. A. Helsen, Annemarie van
der Heijden, Tatsuo Senshu, Wim B. van den Berg, Walther J. van Venrooij,
and Leo A. B. Joosten |
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| Osteoarthritis and Cartilage |
| 2501
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Expression
of Bone Morphogenetic Protein 6 in Healthy and Osteoarthritic Human
Articular Chondrocytes and Stimulation of Matrix Synthesis In Vitro
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K.
Bobacz, R. Gruber, A. Soleiman, L. Erlacher, J. S. Smolen, and W. B.
Graninger |
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| 2509
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Osteoarthritis-Like
Changes and Decreased Mechanical Function of Articular Cartilage in
the Joints of Mice With the Chondrodysplasia Gene (cho) |
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L.
Xu, C. M. Flahiff, B. A. Waldman, D. Wu, B. R. Olsen, L. A. Setton,
and Y. Li |
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| Systemic
Lupus Erythematosus and Autoimmunity
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| 2519
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Hospitalizations
for Coronary Artery Disease Among Patients With Systemic Lupus Erythematosus
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Christine
M. Thorburn and Michael M. Ward |
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| 2524
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Expression
of the Markers BDCA-2 and BDCA-4 and Production of Interferon-[ga] by
Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus |
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Stina
Blomberg, Maija-Leena Eloranta, Mattias Magnusson, Gunnar V. Alm, and
Lars Ronnblom |
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| 2533
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Elevated
Triglycerides and Low Levels of High-Density Lipoprotein as Markers
of Disease Activity in Association With Up-Regulation of the Tumor Necrosis
Factor [ga]/Tumor Necrosis Factor Receptor System in Systemic Lupus
Erythematosus |
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Elisabet
Svenungsson, Iva Gunnarsson, Guo-Zhong Fei, Ingrid E. Lundberg, Lars
Klareskog, and Johan Frostegard |
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| 2541
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Distinct
Mechanisms of Action of Anti-CD154 in Early Versus Late Treatment of
Murine Lupus Nephritis |
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Sergio
A. Quezada, Maria Eckert, Oyedele A. Adeyi, Alan R. Schned, Randolph
J. Noelle, and Christopher M. Burns |
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| 2555
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Antagonist
of Monocyte Chemoattractant Protein 1 Ameliorates the Initiation and
Progression of Lupus Nephritis and Renal Vasculitis in MRL/lpr Mice
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Hitoshi
Hasegawa, Masashi Kohno, Miho Sasaki, Atsushi Inoue, Mitsuko R. Ito,
Miho Terada, Kunio Hieshima, Hiroki Maruyama, Jun-ichi Miyazaki, Osamu
Yoshie, Masato Nose, and Shigeru Fujita |
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| 2567
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HLA-DQA1
Is Not an Apparent Risk Factor for Microchimerism in Patients With Various
Autoimmune Diseases and in Healthy Individuals |
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Carol
M. Artlett, Terrence P. O'Hanlon, Ana M. Lopez, Yeong Wook Song, Frederick
W. Miller, and Lisa G. Rider, for the Childhood Myositis Heterogeneity
Collaborative Study Group |
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| Sjogren's
Syndrome |
| 2573
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Enhanced
Degradation of Proteins of the Basal Lamina and Stroma by Matrix Metalloproteinases
From the Salivary Glands of Sjogren's Syndrome Patients: Correlation
With Reduced Structural Integrity of Acini and Ducts |
|
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Eduardo
Goicovich, Claudio Molina, Paola Perez, Sergio Aguilera, Juan Fernandez,
Nancy Olea, Cecilia Alliende, Cecilia Leyton, Rafael Romo, Lisette Leyton,
and Mar|fia-Julieta Gonzalez |
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| Systemic
Sclerosis |
| 2585
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Genome-Wide
Association Study for Regions of Systemic Sclerosis Susceptibility in
a Choctaw Indian Population With High Disease Prevalence |
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Xiaodong
Zhou, Filemon K. Tan, Ning Wang, Momiao Xiong, Samuel Maghidman, John
D. Reveille, Dianna M. Milewicz, Ranajit Chakraborty, and Frank C. Arnett
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| 2593
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Systemic
Sclerosis Th2 Cells Inhibit Collagen Production by Dermal Fibroblasts
Via Membrane-Associated Tumor Necrosis Factor [ga] |
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Carlo
Chizzolini, Yann Parel, Carmelina De Luca, Alan Tyndall, Anita Akesson,
Agneta Scheja, and Jean-Michel Dayer |
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| 2605
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In
Vivo Analysis of the Apoptosis-Inducing Effect of Anti-Endothelial Cell
Antibodies in Systemic Sclerosis by the Chorionallantoic Membrane Assay
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Miriam
Worda, Roswitha Sgonc, Hermann Dietrich, Harald Niederegger, Roy S.
Sundick, M. Eric Gershwin, and Georg Wick |
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| Childhood
Arthritis |
| 2615
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Predicting
the Onset of Widespread Body Pain Among Children |
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Gareth
T. Jones, Alan J. Silman, and Gary J. Macfarlane |
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| 2622
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Expression
of Myeloid-Related Proteins 8 and 14 in Systemic-Onset Juvenile Rheumatoid
Arthritis |
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Michael
Frosch, Thomas Vogl, Stephan Seeliger, Nico Wulffraat, Wietse Kuis,
Dorothee Viemann, Dirk Foell, Clemens Sorg, Cord Sunderkotter, and Johannes
Roth |
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| Crystal-Induced
Arthritis |
| 2627
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Mutations
in the Amino Terminus of ANKH in Two US Families With Calcium Pyrophosphate
Dihydrate Crystal Deposition Disease |
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Charlene
J. Williams, Adrian Pendleton, Gina Bonavita, Antonio J. Reginato, Anne
E. Hughes, Shelly Peariso, Michael Doherty, Daniel J. McCarty, and Lawrence
M. Ryan |
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| Genetic
Syndromes |
| 2632
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Heterogeneity
Among Patients With Tumor Necrosis Factor Receptor-Associated Periodic
Syndrome Phenotypes |
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Ebun
Aganna, Linda Hammond, Philip N. Hawkins, Anna Aldea, Shane A. McKee,
Hans Kristian Ploos van Amstel, Claudia Mischung, Koichi Kusuhara, Frank
T. Saulsbury, Helen J. Lachmann, Alison Bybee, Elizabeth M. McDermott,
Micaela La Regina, Juan I. Arostegui, Josep M. Campistol, Sharron Worthington,
Kevin P. High, Michael G. Molloy, Nicholas Baker, Jeff L. Bidwell, Jose
L. Castaner, Margo L. Whiteford, P. L. Janssens-Korpola, Raffaele Manna,
Richard J. Powell, Patricia Woo, Pilar Solis, Kirsten Minden, Joost
Frenkel, Jordi Yague, Rita M. Mirakian, Graham A. Hitman, and Michael
F. McDermott |
|
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| 2645
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Favorable
Preliminary Experience With Etanercept in Two Patients With the Hyperimmunoglobulinemia
D and Periodic Fever Syndrome |
|
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Kazuki
Takada, Ivona Aksentijevich, Vijayabhanu Mahadevan, Jane A. Dean, Richard
I. Kelley, and Daniel L. Kastner |
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| Animal
Models |
| 2652
|
A
Highly Selective Inhibitor of I[gk]B Kinase, BMS-345541, Blocks Both
Joint Inflammation and Destruction in Collagen-Induced Arthritis in
Mice |
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Kim
W. McIntyre, David J. Shuster, Kathleen M. Gillooly, Donna M. Dambach,
Mark A. Pattoli, Pin Lu, Xia-Di Zhou, Yuping Qiu, F. Christopher Zusi,
and James R. Burke |
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| 2660
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Vegfb
Gene Knockout Mice Display Reduced Pathology and Synovial Angiogenesis
in Both Antigen-Induced and Collagen-Induced Models of Arthritis |
|
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Arne
W. Mould, Ian D. Tonks, Marian M. Cahill, Allison R. Pettit, Ranjeny
Thomas, Nicholas K. Hayward, and Graham F. Kay |
|
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| 2670
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Prevention
of the Onset and Progression of Collagen-Induced Arthritis in Rats by
the Potent p38 Mitogen-Activated Protein Kinase Inhibitor FR167653
|
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Masataka
Nishikawa, Akira Myoui, Tetsuya Tomita, Koichiro Takahi, Akihide Nampei,
and Hideki Yoshikawa |
|
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| 2682
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Suppression
of Arthritic Bone Destruction by Adenovirus-Mediated Dominant-Negative
Ras Gene Transfer to Synoviocytes and Osteoclasts |
|
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Aiichiro
Yamamoto, Akira Fukuda, Hiroaki Seto, Tsuyoshi Miyazaki, Yuho Kadono,
Yasuhiro Sawada, Ichiro Nakamura, Hideki Katagiri, Tomoichiro Asano,
Yoshiya Tanaka, Hiromi Oda, Kozo Nakamura, and Sakae Tanaka |
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| Letters |
| 2693
|
Interpretation
of Trial Methodology Not Always Easy: Comment on the Editorial by Landewe
|
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Johannes
W. G. Jacobs and Johannes W. J. Bijlsma |
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| 2694
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Reply
|
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Robert
B. M. Landewe |
|
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| 2694
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Rate
of Death Due to Leukemia/Lymphoma in Patients With Rheumatoid Arthritis
|
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Frederick
Wolfe and James F. Fries |
|
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| 2695
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Polymorphism
in the Stromelysin 1 (Matrix Metalloproteinase 3) Promoter Gene and
Severity of Rheumatoid Arthritis: Comment on the Article by Constantin
et al |
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Marco
Massarotti, Bianca Marasini, Antonio Marchesoni, Marco Arreghini, and
Maria Luisa Biondi |
|
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| 2696
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Hematopoietic
Stem Cell Transplantation for Severe and Refractory Lupus: Comment on
the Article by Traynor et al |
|
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Alberto
M. Marmont |
|
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| 2697
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Reply
|
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Ann
Traynor, Walter Barr, Robert Rosa, Julianne Rodriguez, Yu Oyama, Mary
Brush, and Richard Burt |
|
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| 2697
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Development
of Systemic Lupus Erythematosus in a Patient With Congenital Heart Block
|
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Eugen
Feist, Rolf Keitzer, Kerstin Gerhold, Linn Horvath, Marie Wahren-Herlenius,
and Thomas Dorner |
|
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| 2699
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Reply
|
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Anca
Dinu Askanase, Robert M. Clancy, and Jill P. Buyon |
|
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| 2700
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Assessment
of Brachial Artery Flow-Mediated Vasodilatation: Comment on the Article
by Van Doornum et al |
|
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Simona
Marchesi, Gaetano Vaudo, Graziana Lupattelli, and Elmo Mannarino |
|
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| 2700
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Reply
|
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S.
Van Doornum and I. P. Wicks |
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| ACR
Announcements |
Cover
image: The figure on the cover (from Sundarrajan et al, page 2457) illustrates
colocalization of the kinases MKK-4, MKK-7, and JNK in cultured fibroblast-like
synoviocytes, using immunofluorescence microscopy. Each protein is stained
with a labeled antibody of a different color. These kinases play an
important role in regulating gene expression leading to joint destruction
in rheumatoid arthritis. Colocalization is consistent with the formation
of a signaling complex that is functionally active and can be targeted
for therapy. |
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