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Special
Articles
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1471 |
Editorial:
Does Vascular Endothelial Growth Factor Play a Role in Interleukin-6
Receptor Antagonist Therapy for Rheumatoid Arthritis?
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Julieta
Gentiletti and Roy A. Fava |
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1475 |
Editorial:
C-Reactive Protein as a Regulator of Autoimmunity and Inflammation
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Terry
W. Du Clos |
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1478 |
Editorial:
The Role of Leukotrienes in Alveolitis Associated With Scleroderma
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Robert
W. Simms and Joseph H. Korn |
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1481 |
Perspective:
Add-On or Step-Up Trials for New Drug Development in Rheumatoid Arthritis:
A New Standard?
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Maarten
Boers |
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1484 |
Review:
Rituximab Therapy and Autoimmune Disorders: Prospects for Anti-B Cell
Therapy
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Gregg
J. Silverman and Stuart Weisman |
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Rheumatoid
Arthritis
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1493 |
Etanercept
Added to Background Methotrexate Therapy in Patients With Rheumatoid
Arthritis: Continued Observations
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Joel
M. Kremer, Michael E. Weinblatt, Arthur D. Bankhurst, Ken J. Bulpitt,
Roy M. Fleischmann, Christopher G. Jackson, Kelly M. Atkins, Anyang
Feng, and Daniel J. Burge |
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1500 |
Clinical
Responses to Tumor Necrosis Factor [alpha] Antagonists Do Not Show a
Bimodal Distribution: Data From the Stockholm Tumor Necrosis Factor
[alpha] Followup Registry
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Ronald
F. van Vollenhoven and Lars Klareskog |
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1504 |
Long-Term
Anti-Tumor Necrosis Factor Antibody Therapy in Rheumatoid Arthritis
Patients Sensitizes the Pituitary Gland and Favors Adrenal Androgen
Secretion
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Rainer
H. Straub, Georg Pongratz, Jurgen Scholmerich, Frieder Kees, Thomas
F. Schaible, Christian Antoni, Joachim R. Kalden, and Hanns-Martin Lorenz |
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1513 |
The
Efficacy and Safety of Leflunomide in Patients With Active Rheumatoid
Arthritis: A Five-Year Followup Study
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J.
R. Kalden, M. Schattenkirchner, H. Sorensen, P. Emery, C. Deighton,
B. Rozman, and F. Breedveld |
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1521 |
Anti-Interleukin-6
Receptor Antibody Therapy Reduces Vascular Endothelial Growth Factor
Production in Rheumatoid Arthritis
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Hideko
Nakahara, Jian Song, Masamichi Sugimoto, Keisuke Hagihara, Tadamitsu
Kishimoto, Kazuyuki Yoshizaki, and Norihiro Nishimoto |
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1530 |
Predicting
Mortality in Patients With Rheumatoid Arthritis
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Frederick
Wolfe, Kaleb Michaud, Olaf Gefeller, and Hyon K. Choi |
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1543 |
Lymphoma
Subtypes in Patients With Rheumatoid Arthritis: Increased Proportion
of Diffuse Large B Cell Lymphoma
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Eva
Baecklund, Christer Sundstrom, Anders Ekbom, Anca I. Catrina, Peter
Biberfeld, Nils Feltelius, and Lars Klareskog |
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1551 |
Selective
Inhibition of Cyclooxygenase 2-Generated Prostaglandin E2 Synthesis
in Rheumatoid Arthritis Synoviocytes by Taurine Chloramine
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Ewa
Kontny, Weronika Rudnicka, Jacek Kowalczewski, Janusz Marcinkiewicz,
and Wlodzimierz Maslinski |
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Osteoarthritis
and Cartilage
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1556 |
Asymmetric
Knee Loading in Advanced Unilateral Hip Osteoarthritis
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Najia
Shakoor, Debra E. Hurwitz, Joel A. Block, Susan Shott, and John P. Case |
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1562 |
Hsp70
Prevents Nitric Oxide-Induced Apoptosis in Articular Chondrocytes
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Ryu
Terauchi, Kenji A. Takahashi, Yuji Arai, Takumi Ikeda, Suzuyo Ohashi,
Jiro Imanishi, Osam Mazda, and Toshikazu Kubo |
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1569 |
Mediation
of Interleukin-1[beta]-Induced Transforming Growth Factor [beta]1 Expression
by Activator Protein 4 Transcription Factor in Primary Cultures of Bovine
Articular Chondrocytes: Possible Cooperation With Activator Protein
1
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R.
Andriamanalijaona, N. Felisaz, S.-J. Kim, K. King-Jones, M. Lehmann,
J.-P. Pujol, and K. Boumediene |
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1582 |
In
Vivo Selective Inhibition of Mitogen-Activated Protein Kinase Kinase
1/2 in Rabbit Experimental Osteoarthritis Is Associated With a Reduction
in the Development of Structural Changes
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Jean-Pierre
Pelletier, Julio C. Fernandes, Julie Brunet, Florina Moldovan, Denis
Schrier, Craig Flory, and Johanne Martel-Pelletier |
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1594 |
Effects
of Antiinflammatory Drugs on Arthritic Cartilage: A High-Frequency Quantitative
Ultrasound Study in Rats
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Britta
Jaffre, Astrid Watrin, Damien Loeuille, Pierre Gillet, Patrick Netter,
Pascal Laugier, and Amena Saied |
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Systemic
Lupus Erythematosus and Autoimmunity
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1602 |
Delayed
Lupus Onset in (NZB x NZW)F1 Mice Expressing a Human C-Reactive Protein
Transgene
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Alexander
J. Szalai, Casey T. Weaver, Mark A. McCrory, Frederik W. van Ginkel,
Rachael M. Reiman, John F. Kearney, Tony N. Marion, and John E. Volanakis |
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1612 |
Differential
Control of CD22 Ligand Expression on B and T Lymphocytes, and Enhanced
Expression in Murine Systemic Lupus
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Frederic
Lajaunias, Akinori Ida, Shuichi Kikuchi, Liliane Fossati-Jimack, Eduardo
Martinez-Soria, Thomas Moll, Che-Leung Law, and Shozo Izui |
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1622 |
A
Thrombin-Cross-Reactive Anticardiolipin Antibody Binds to and Inhibits
the Anticoagulant Function of Activated Protein C
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Kwan-Ki
Hwang, Cheng-De Yang, Weihong Yan, Jennifer M. Grossman, Bevra H. Hahn,
and Pojen P. Chen |
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Childhood
Arthritis
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1631 |
Frequent
Infection With a Viral Pathogen, Parvovirus B19, in Rheumatic Diseases
of Childhood
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Hartwig
W. Lehmann, Antje Knoll, Rolf-Michael Kuster, and Susanne Modrow |
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Systemic
Sclerosis
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1639 |
Elevated
Levels of Leukotriene B4 and Leukotriene E4 in Bronchoalveolar Lavage
Fluid From Patients With Scleroderma Lung Disease
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Otylia
Kowal-Bielecka, Oliver Distler, Krzysztof Kowal, Zenon Siergiejko, Justyna
Chwiecko, Agnieszka Sulik, Renate E. Gay, Anna Bodzenta |fLukaszyk,
Steffen Gay, and Stanis|flaw Sierakowski |
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1647 |
Anti-c-Mpl
(Thrombopoietin Receptor) Autoantibody-Induced Amegakaryocytic Thrombocytopenia
in a Patient With Systemic Sclerosis
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Yasuhiro
Katsumata, Takahiro Suzuki, Masataka Kuwana, Yutaka Hattori, Satoshi
Akizuki, Hitoshi Sugiura, and Yasuo Matsuoka |
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1652 |
Epidermal
Growth Factor Up-Regulates Expression of Transforming Growth Factor
[beta] Receptor Type II in Human Dermal Fibroblasts by Phosphoinositide
3-Kinase/Akt Signaling Pathway: Resistance to Epidermal Growth Factor
Stimulation in Scleroderma Fibroblasts
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Kenichi
Yamane, Hironobu Ihn, and Kunihiko Tamaki |
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Spondylarthropathy
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1667 |
Six-Month
Results of a Double-Blind, Placebo-Controlled Trial of Etanercept Treatment
in Patients With Active Ankylosing Spondylitis
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J.
Brandt, A. Khariouzov, J. Listing, H. Haibel, H. Sorensen, L. Grassnickel,
M. Rudwaleit, J. Sieper, and J. Braun |
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Psoriatic
Arthritis
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1676 |
Increased
Perivascular Synovial Membrane Expression of Myeloid-Related Proteins
in Psoriatic Arthritis
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David
Kane, Johannes Roth, Michael Frosch, Thomas Vogl, Barry Bresnihan, and
Oliver FitzGerald |
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Fibromyalgia
and Pain
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1686 |
Association
of Widespread Body Pain With an Increased Risk of Cancer and Reduced
Cancer Survival: A Prospective, Population-Based Study
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John
McBeth, Alan J. Silman, and Gary J. Macfarlane |
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Experimental
Arthritis and Therapeutics
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1693 |
High
Mobility Group Box Chromosomal Protein 1, a DNA Binding Cytokine, Induces
Arthritis
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Rille
Pullerits, Ing-Marie Jonsson, Margareta Verdrengh, Maria Bokarewa, Ulf
Andersson, Helena Erlandsson-Harris, and Andrej Tarkowski |
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1701 |
Influence
of Stimulatory and Suppressive DNA Motifs on Host Susceptibility to
Inflammatory Arthritis
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Rainald
A. Zeuner, Daniela Verthelyi, Mayda Gursel, Ken J. Ishii, and Dennis
M. Klinman |
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1708 |
Sex
Effect on Clinical and Immunologic Quantitative Trait Loci in a Murine
Model of Rheumatoid Arthritis
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Vyacheslav
A. Adarichev, Andrew B. Nesterovitch, Tamas Bardos, Darci Biesczat,
Raman Chandrasekaran, Csaba Vermes, Katalin Mikecz, Alison Finnegan,
and Tibor T. Glant |
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1721 |
Blockade
of Parathyroid Hormone-Related Protein Prevents Joint Destruction and
Granuloma Formation in Streptococcal Cell Wall-Induced Arthritis
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J.
L. Funk, J. Chen, K. J. Downey, S. M. Davee, and G. Stafford |
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1732 |
Effect
of Minodronic Acid (ONO-5920) on Bone Mineral Density and Arthritis
in Adult Rats With Collagen-Induced Arthritis
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Itsuro
Yamane, Hiroshi Hagino, Toru Okano, Makoto Enokida, Daisuke Yamasaki,
and Ryota Teshima |
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1742 |
Broad-Spectrum
Matrix Metalloproteinase Inhibitor Marimastat-Induced Musculoskeletal
Side Effects in Rats
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Richard
Renkiewicz, Luping Qiu, Charles Lesch, Xin Sun, Radhika Devalaraja,
Theresa Cody, Eric Kaldjian, Howard Welgus, and Vijaykumar Baragi |
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1750 |
Growth
Plate Damage, a Feature of Juvenile Idiopathic Arthritis, Can Be Induced
by Adenoviral Gene Transfer of Oncostatin M: A Comparative Study in
Gene-Deficient Mice
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Alfons
S. K. de Hooge, Fons A. J. van de Loo, Miranda B. Bennink, Onno J. Arntz,
Theo J. W. Fiselier, Marcel J. A. M. Franssen, Leo A. B. Joosten, Peter
L. E. M. van Lent, Carl D. Richards, and Wim B. van den Berg |
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Concise
Communication
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1762 |
Female
Sex Increases Risk for Rheumatoid Arthritis Only in Individuals Encoding
Low-Risk HLA-DRB1 Alleles
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Niek
de Vries, Paul P. Tak, Henk Tijssen, Piet L. C. M. van Riel, and Leo
B. A. van de Putte |
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1763 |
Erratum
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Omission
of grant support information in article by Yasuda et al (Arthritis Rheum,
May 2003) |
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Letters
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1764 |
New
American Academy of Ophthalmology Recommendations on Screening for Hydroxychloroquine
Retinopathy
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Michael
F. Marmor |
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1764 |
Report
of an Additional Case of Anti-Tumor Necrosis Factor Therapy and Listeria
monocytogenes Infection: Comment on the Letter by Gluck et al
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Angel
Garcia Aparicio, Santiago Munoz-Fernandez, Gema Bonilla, Ambrosio Miralles,
Victor Cerdeno, and Emilio Martin-Mola |
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1765 |
Reply
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Thomas
Gluck and U. Muller-Ladner |
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1766 |
Pseudoscleroderma
Associated With Transforming Growth Factor [beta]1-Producing Advanced
Gastric Carcinoma: Comment on the Article by Varga
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Takao
Fujii, Tsuneyo Mimori, Noriko Kimura, Shinji Satoh, and Michito Hirakata |
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1767 |
Reply
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John
Varga |
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1768 |
Emerging
Clinical Spectrum of Tumor Necrosis Factor Receptor-Associated Periodic
Syndrome: Comment on the Articles by Hull et al and Dode et al
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E.
Drewe, P. C. Lanyon, and R. J. Powell |
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1769 |
Reply
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Keith
M. Hull and Daniel L. Kastner |
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Clinical
Images
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1770 |
Tumoral
Calcinosis Associated With Sarcoidosis
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John
D. Carter and Elizabeth Warner |
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Cover
image:
The figure on the cover (from Szalai et al, page 1607)
illustrates immunofluorescence staining for mouse IgG (red) and mouse
C3 (green) in the kidney of an autoimmune (NZB x NZW) mouse expressing
a human C-reactive protein transgene. This study points to the role
of C-reactive protein in the clearance of immune complexes and its potential
role in modifying nephritis in systemic lupus erythematosus. |