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Special
Articles
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2265
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Editorial: Understanding
the Dynamics Between Ethnicity and Health Care: Another Role for Health
Services Research in Chronic Disease Management
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John R. Feussner
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2268
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Review: Extravascular
Coagulation and the Plasminogen Activator/Plasmin System in Rheumatoid
Arthritis
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Nathalie Busso and
John A. Hamilton
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2280
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Conference Summary:
Ethnic Health Disparities in Arthritis and Musculoskeletal Diseases: Report
of a Scientific Conference
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Joanne M. Jordan,
Reva Lawrence, Raynard Kington, Patricia Fraser, Elizabeth Karlson, Kate
Lorig, and Matthew H. Liang
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Rheumatoid
Arthritis
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2287
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Frequency of Infection
in Patients With Rheumatoid Arthritis Compared With Controls: A Population-Based
Study
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Michele F. Doran,
Cynthia S. Crowson, Gregory R. Pond, W. Michael O'Fallon, and Sherine
E. Gabriel
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2294
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Predictors of Infection
in Rheumatoid Arthritis
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Michele F. Doran,
Cynthia S. Crowson, Gregory R. Pond, W. Michael O'Fallon, and Sherine
E. Gabriel
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2301
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A Pilot Randomized
Trial Comparing CD34-Selected Versus Unmanipulated Hemopoietic Stem Cell
Transplantation for Severe, Refractory Rheumatoid Arthritis
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John Moore, Peter
Brooks, Sam Milliken, Jim Biggs, David Ma, Malcolm Handel, Paul Cannell,
Rob Will, Simon Rule, David Joske, Bob Langlands, Kerry Taylor, Joe O'Callaghan,
Jeff Szer, Ian Wicks, Geoff McColl, Frances Passeullo, and John Snowden
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2310
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Modeling the Progression
of Rheumatoid Arthritis: A Two-Country Model to Estimate Costs and Consequences
of Rheumatoid Arthritis
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Gisela Kobelt, Linus
Jonsson, Peter Lindgren, Adam Young, and Kerstin Eberhardt Tyson Holmes,
and Bonnie Bruce
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2320
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HLA-DRB1 Genotype
Associations in 793 White Patients From a Rheumatoid Arthritis Inception
Cohort: Frequency, Severity, and Treatment Bias
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James F. Fries, Frederick
Wolfe, Raymond Apple, Henry Erlich, Teodorica Bugawan,
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2330
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CD13/Aminopeptidase
N-Induced Lymphocyte Involvement in Inflamed Joints of Patients With Rheumatoid
Arthritis
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Teruki Shimizu, Kenji
Tani, Kayoko Hase, Hirohisa Ogawa, Luping Huang, Fumio Shinomiya, and
Saburo Sone
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2339
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Epitope-Specific
Recognition of Type II Collagen by Rheumatoid Arthritis Antibodies Is
Shared With Recognition by Antibodies That Are Arthritogenic in Collagen-Induced
Arthritis in the Mouse
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Harald Burkhardt,
Tobias Koller, Ake Engstrom, Kutty Selva Nandakumar, Javier Turnay, Hans
G. Kraetsch, Joachim R. Kalden, and Rikard Holmdahl
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Osteoarthritis
and Cartilage
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2349
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Detection of Nitrotyrosine
in Aging and Osteoarthritic Cartilage: Correlation of Oxidative Damage
With the Presence of Interleukin-1[beta] and With Chondrocyte Resistance
to Insulin-Like Growth Factor 1
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Richard F. Loeser,
Cathy S. Carlson, Marcello Del Carlo, and Ada Cole
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2358
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The Insulin-Like
Growth Factor Binding Proteins in Uncultured Human Cartilage: Increases
in Insulin-Like Growth Factor Binding Protein 3 During Osteoarthritis
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Teresa I. Morales
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2368
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Fibronectin Fragments
and Blocking Antibodies to [alpha]2[beta]1 and [alpha]5[beta]1 Integrins
Stimulate Mitogen-Activated Protein Kinase Signaling and Increase Collagenase
3 (Matrix Metalloproteinase 13) Production by Human Articular Chondrocytes
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Christopher B. Forsyth,
Judit Pulai, and Richard F. Loeser
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Systemic
Lupus Erythematosus and Autoimmunity
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2377
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Long-Term Followup
of Children With Neonatal Lupus and Their Unaffected Siblings
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Victor Martin, Lela
A. Lee, Anca D. Askanase, Margaret Katholi, and Jill P. Buyon
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2384
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Autoantibodies
Against Granulocyte Colony-Stimulating Factor in Felty's Syndrome and
Neutropenic Systemic Lupus Erythematosus
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Bernhard Hellmich,
Elena Csernok, Helmut Schatz, Wolfgang L. Gross, and Armin Schnabel
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Childhood
Arthritis
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2392
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Long-Term Outcome
in Patients With Juvenile Idiopathic Arthritis
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Kirsten Minden, Martina
Niewerth, Joachim Listing, Thomas Biedermann, Matthias Bollow, Monika
Schntube, and Angela Zink
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2402
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Mutation Screening
of the Macrophage Migration Inhibitory Factor Gene: Positive Association
of a Functional Polymorphism of Macrophage Migration Inhibitory Factor
With Juvenile Idiopathic Arthritis
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Rachelle Donn, Zaynab
Alourfi, Fabrizio De Benedetti, Cristina Meazza, Eleftheria Zeggini, Mark
Lunt, Adam Stevens, Emma Shelley, Rebecca Lamb, the British Paediatric
Rheumatology Study Group, William E. R. Ollier, Wendy Thomson, and David
Ray
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Systemic Sclerosis
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2410
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Measuring Disease
Activity and Functional Status in Patients With Scleroderma and Raynaud's
Phenomenon
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Peter A. Merkel, Karen
Herlyn, Richard W. Martin, Jennifer J. Anderson, Maureen D. Mayes, Patrice
Bell, Joseph H. Korn, Robert W. Simms, Mary Ellen Csuka, Thomas A. Medsger,
Jr., Naomi F. Rothfield, Michael H. Ellman, David H. Collier, Arthur Weinstein,
Daniel E. Furst, Sergio A. Jimenez, Barbara White, James R. Seibold, and
Fredrick M. Wigley, for the Scleroderma Clinical Trials Consortium
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2421
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Increased Transcriptional
Activities of Transforming Growth Factor [beta] Receptors in Scleroderma
Fibroblasts
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Kenichi Yamane, Hironobu
Ihn, Masahide Kubo, and Kunihiko Tamaki
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Surgical Treatment
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2429
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Differences in
Expectations of Outcome Mediate African American/White Patient Differences
in ``Willingness'' to Consider Joint Replacement
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Said A. Ibrahim, Laura
A. Siminoff, Christopher J. Burant, and C. Kent Kwoh
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2436
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Contribution of
Hospital Characteristics to the Volume-Outcome Relationship: Dislocation
and Infection Following Total Hip Replacement Surgery
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Daniel H. Solomon,
Elena Losina, John A. Baron, Anne H. Fossel, Edward Guadagnoli, Elizabeth
A. Lingard, Andrew Miner, Charlotte B. Phillips, and Jeffrey N. Katz
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Genetics
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2445
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Association of
Mutations in the NALP3/CIAS1/PYPAF1 Gene With a Broad Phenotype Including
Recurrent Fever, Cold Sensitivity, Sensorineural Deafness, and AA Amyloidosis
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Ebun Aganna, Fabio
Martinon, Philip N. Hawkins, John B. Ross, Daniel C. Swan, David R. Booth,
Helen J. Lachmann, Roxanne Gaudet, Patricia Woo, Conleth Feighery, Finbarr
E. Cotter, Margot Thome, Graham A. Hitman, Jurg Tschopp, and Michael F.
McDermott
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Animal Models
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2453
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Reduced Susceptibility
to Collagen-Induced Arthritis in DBA/1J Mice Expressing the TSG-6 Transgene
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C. Mindrescu, A. A.
M. Dias, R. J. Olszewski, M. J. Klein, L. F. L. Reis, and H.-G. Wisniewski
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2465
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Mice Lacking Endogenous
Major Histocompatibility Complex Class II Develop Arthritis Resembling
Psoriatic Arthritis at an Advanced Age
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Tamas Bardos, Jian
Zhang, Katalin Mikecz, Chella S. David, and Tibor T. Glant
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2476
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Antiarthritic Activity
of an Orally Active C5a Receptor Antagonist Against Antigen-Induced Monarticular
Arthritis in the Rat
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Trent M. Woodruff,
Anna J. Strachan, Nathan Dryburgh, Ian A. Shiels, Robert C. Reid, David
P. Fairlie, and Stephen M. Taylor
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2486
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Lectin-Like Oxidized
Low-Density Lipoprotein Receptor 1 Mediates Leukocyte Infiltration and
Articular Cartilage Destruction in Rat Zymosan-Induced Arthritis
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Takefumi Nakagawa,
Masao Akagi, Hajime Hoshikawa, Mingyi Chen, Tadashi Yasuda, Shogo Mukai,
Kunitaka Ohsawa, Tomoh Masaki, Takashi Nakamura, and Tatsuya Sawamura
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2495
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Effect of Oral
Glucosamine on Cartilage and Meniscus in Normal and Chymopapain-Injected
Knees of Young Rabbits
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Theodore R. Oegema,
Jr., Laurel B. Deloria, John D. Sandy, and David A. Hart
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2504
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Antiinflammatory
Effect of Retrovirally Transfected Interleukin-10 on Monosodium Urate
Monohydrate Crystal-Induced Acute Inflammation in Murine Air Pouches
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Yousuke Murakami,
Tohru Akahoshi, Shinichi Kawai, Matsuhisa Inoue, and Hidero Kitasato
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2514
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Adeno-Associated
Virus-Mediated Osteoprotegerin Gene Transfer Protects Against Particulate
Polyethylene-Induced Osteolysis in a Murine Model
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Shang-You Yang, Lois
Mayton, Bin Wu, J. Jeffrey Goater, Edward M. Schwarz, and Paul H. Wooley
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2524
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Tissue-Engineered
Composites for the Repair of Large Osteochondral Defects
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Dirk Schaefer, Ivan
Martin, G. Jundt, Joachim Seidel, Michael Heberer, Alan Grodzinsky, Ingrid
Bergin, Gordana Vunjak-Novakovic, and Lisa E. Freed
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Concise Communication
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2535
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HLA-DRB1*01 and
Macrophagic Myofasciitis
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Sandrine Guis, Jean-Francois
Pellissier, Francois Nicoli, Denis Reviron, Jean-Pierre Mattei, Romain
K. Gherardi, Jean Pelletier, Gilles Kaplanski, Dominique Figarella-Branger,
and Jean Roudier
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Clinical Image
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2537
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A Hungry Histiocyte:
Lupus-Related Hemophagocytic Syndrome
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Michael S. Lloyd,
Kelly J. Bethel, and Ken D. Pischel
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Letters
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2538
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Microchimerism
in Systemic Sclerosis: Comment on the Article by Johnson et al
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P. J. Roberts-Thomson,
J. G. Walker, P. Hakendorf, M. D. Smith, and M. J. Ahern
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2538
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Reply
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K. L. Johnson, D.
W. Bianchi, and J. L. Nelson
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2539
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Highly Elevated
Serum Levels of Interleukin-18 in Systemic Juvenile Idiopathic Arthritis
but Not in Other Juvenile Idiopathic Arthritis Subtypes or in Kawasaki
Disease: Comment on the Article by Kawashima et al
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Nobuaki Maeno, Syuji
Takei, Yuichi Nomura, Hiroyuki Imanaka, Masashi Hokonohara, and Koichiro
Miyata
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2541
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Reply
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Masahiro Yamamura,
Masanori Kawashima, and Hirofumi Makino
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2542
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Treatment With
Gonadotropin-Releasing Hormone Agonists and Prevention of Multiple Gestations
in Lupus or Antiphospholipid Syndrome Patients Undergoing In Vitro Fertilization:
Comment on the Article by Guballa et al
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Zeev Blumenfeld
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2542
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Reply
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Michael D. Lockshin,
Lisa R. Sammaritano, and Sergio Schwartzman
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2543
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Differentiation
of Hyaluronate Products by Qualitative Differences in Their Immunogenicity
in Rabbits: Possible Mechanism for Product-Specific Severe Adverse Reactions?
Comment on the Article by Martens
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William Bucher, Todd
Otto, and Max I. Hamburger
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2544
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Reply
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Peter B. Martens
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2545
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Silicone Breast
Implants Do Not Cause Rheumatic Diseases, but Can They Influence Them?
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Daniel J. Wallace
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2545
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Treatment of Fibromyalgia
With Sibutramine Hydrochloride Monohydrate: Comment on the Article by
Goldenberg et al
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Mark Palangio, John
A. Flores, and Steven V. Joyal
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2546
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Reply
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Don Goldenberg and
Tej Sandhu
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2546
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Use of Triamcinolone
Hexacetonide for the Treatment of Osteoarthritis of the Hip: Comment on
the Letter by Margules
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Charles Kahn
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2547
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Reply
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Kenneth R. Margules
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2547
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Laboratory Tests
and ``Likelihood Ratios'': Comment on the Editorial by Kavanaugh
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A. S. Russell
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2547
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Reply
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Arthur Kavanaugh
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2547
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The Neural Network
as a Predictor of Cancer in Patients With Inflammatory Myopathies
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Albert Selva-O'Callaghan,
Tilman Mijares-Boeckh-Behrens, Roser Solans-Laque, Moises Labrador-Horrillo,
Enrique Romero-Merino, Jose M. Sopena-Sisquella, and Miquel Vilardell-Tarres
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ACR Announcements
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23A
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Cover image: The
figure on the cover (from Yang et al, page 2519) illustrates a histologic
section from a bone-implanted air pouch system in the mouse, used to evaluate
the effects of virus-mediated gene transfer with osteoprotegerin on particulate
polyethylene-induced osteolysis. The section is stained with trichrome
to show bone collagen content. This system is important in evaluating
candidate molecules to treat or prevent debris-associated osteolysis and
loosening of prostheses.
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