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Special
Articles
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1699
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Editorial: Cell
Death, Autoantigen Cleavage, and Autoimmunity
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K. Michael Pollard
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1703
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Review: Scleroderma
and Smads: Dysfunctional Smad Family Dynamics Culminating in Fibrosis
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John Varga
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Rheumatoid
Arthritis
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1714
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Atherosclerosis
in Rheumatoid Arthritis: Morphologic Evidence Obtained by Carotid Ultrasound
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Yong-Beom Park,
Chul-Woo Ahn, Hyon K. Choi, Seung-Hoon Lee, Byung-Hyun In, Hyun-Chul
Lee, Chung-Mo Nam, and Soo-Kon Lee
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1720
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Bone Loss in
Patients With Rheumatoid Arthritis: Results From a Population-Based
Cohort of 366 Patients Followed Up for Two Years
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Glenn Haugeberg,
Ragnhild E. Orstavik, Till Uhlig, Jan A. Falch, Johan I. Halse, and
Tore K. Kvien
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1729
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An Epidemiologic
Study of Trends in Prevalence of Rheumatoid Factor Seropositivity in
Pima Indians: Evidence of a Decline Due to Both Secular and Birth-Cohort
Influences
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Ian Enzer, Graham
Dunn, Lennart Jacobsson, Peter H. Bennett, William C. Knowler, and Alan
Silman
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1735
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Benefit of an
Extract of Tripterygium Wilfordii Hook F in Patients With Rheumatoid
Arthritis: A Double-Blind, Placebo-Controlled Study
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Xuelian Tao, Jean
Younger, Fred Z. Fan, Betty Wang, and Peter E. Lipsky
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1744
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High Levels of
Osteoprotegerin and Soluble Receptor Activator of Nuclear Factor [Kappa]B
Ligand in Serum of Rheumatoid Arthritis Patients and Their Normalization
After Anti-Tumor Necrosis Factor [alpha] Treatment
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Maria Ziolkowska,
Mariola Kurowska, Anna Radzikowska, Grazyna Luszczykiewicz, Piotr Wiland,
Wojciech Dziewczopolski, Anna Filipowicz-Sosnowska, Jacek Pazdur, Jacek
Szechinski, Jacek Kowalczewski, Maria Rell-Bakalarska, and Wlodzimierz
Maslinski
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1754
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Stromelysin 1
(Matrix Metalloproteinase 3) and HLA-DRB1 Gene Polymorphisms: Association
With Severity and Progression of Rheumatoid Arthritis in a Prospective
Study
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Arnaud Constantin,
Valerie Lauwers-Cances, Frederique Navaux, Michel Abbal, Joost van Meerwijk,
Bernard Mazieres, Anne Cambon-Thomsen, and Alain Cantagrel
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1763
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A Subset of Natural
Killer Cells Is Greatly Expanded Within Inflamed Joints
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Nicola Dalbeth and
Margaret F. C. Callan
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Osteoarthritis
and Cartilage
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1773
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Very Low Prevalence
of Hip Osteoarthritis Among Chinese Elderly in Beijing, China, Compared
With Whites in the United States: The Beijing Osteoarthritis Study
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Michael C. Nevitt,
Ling Xu, Yuqing Zhang, Li-Yung Lui, Wei Yu, Nancy E. Lane, Mingwei Qin,
Marc C. Hochberg, Steven R. Cummings, and David T. Felson
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1780
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Finer Linkage
Mapping of Primary Hip Osteoarthritis Susceptibility on Chromosome 11q
in a Cohort of Affected Female Sibling Pairs
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Kay Chapman, Zehra
Mustafa, Barbara Dowling, Lorraine Southam, Andrew Carr, and John Loughlin
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1784
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Avoidance of
Activity and Disability in Patients With Osteoarthritis of the Knee:
The Mediating Role of Muscle Strength
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M. P. M. Steultjens,
J. Dekker, and J. W. J. Bijlsma
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1789
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Cyclooxygenase
2-Dependent Prostaglandin E2 Modulates Cartilage Proteoglycan Degradation
in Human Osteoarthritis Explants
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Medora M. Hardy,
Karen Seibert, Pamela T. Manning, Mark G. Currie, B. Mark Woerner, Dorothy
Edwards, Alane Koki, and Catherine S. Tripp
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1804
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Study of the
Role of Leukotriene B4 in Abnormal Function of Human Subchondral Osteoarthritis
Osteoblasts: Effects of Cyclooxygenase and/or 5-Lipoxygenase Inhibition
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Yosabeth Paredes,
Frederic Massicotte, Jean-Pierre Pelletier, Johanne Martel-Pelletier,
Stefan Laufer, and Daniel Lajeunesse
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1813
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Use of Joint
Fluid Analysis for Determining Cartilage Damage in Osteonecrosis of
the Knee
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Tomoyuki Saito,
Ryouhei Takeuchi, Shigeyuki Mitsuhashi, Masaaki Uesugi, Takuji Yoshida,
and Tomihisa Koshino
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1820
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Systemic Lupus
Erythematosus and Autoimmunity Effects of Prasterone on Corticosteroid
Requirements of Women With Systemic Lupus Erythematosus: A Double-Blind,
Randomized, Placebo-Controlled Trial
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Michelle A. Petri,
Robert G. Lahita, Ronald F. van Vollenhoven, Joan T. Merrill, Michael
Schiff, Ellen M. Ginzler, Vibeke Strand, Arlene Kunz, Kenneth J. Gorelick,
and Kenneth E. Schwartz, for the GL701 Lupus Study Group
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1830
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Hormonal and
Reproductive Risk Factors for Development of Systemic Lupus Erythematosus:
Results of a Population-Based, Case-Control Study
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Glinda S. Cooper,
Mary Anne Dooley, Edward L. Treadwell, E. William St.Clair, and Gary
S. Gilkeson
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1840
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Occupational
Exposure to Crystalline Silica and Risk of Systemic Lupus Erythematosus:
A Population-Based, Case-Control Study in the Southeastern United States
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Christine G. Parks,
Glinda S. Cooper, Leena A. Nylander-French, Wayne T. Sanderson, John
M. Dement, Philip L. Cohen, Mary Anne Dooley, Edward L. Treadwell, E.
William St.Clair, Gary S. Gilkeson, Jane A. Hoppin, and David A. Savitz
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Childhood
Arthritis
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1851
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Increased Prevalence
of Familial Autoimmunity in Simplex and Multiplex Families With Juvenile
Rheumatoid Arthritis
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Sampath Prahalad,
Edith S. Shear, Susan D. Thompson, Edward H. Giannini, and David N.
Glass
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Systemic Sclerosis
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1857
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Dysregulation
of Transforming Growth Factor [beta] Signaling in Scleroderma: Overexpression
of Endoglin in Cutaneous Scleroderma Fibroblasts
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A. Leask, D. J.
Abraham, D. R. Finlay, A. Holmes, D. Pennington, X. Shi-Wen, Y. Chen,
K. Venstrom, X. Dou, M. Ponticos, C. Black, J. K. Jackman, P. R. Findell,
and M. K. Connolly
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1866
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Development of
a CENP-A/CENP-B-Specific Immune Response in a Patient With Systemic
Sclerosis
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Michael Mahler,
Rudolf Mierau, Ekkehard Genth, and Martin Blthner
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1873
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Recognition of
Granzyme B-Generated Autoantigen Fragments in Scleroderma Patients With
Ischemic Digital Loss
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Lionel Schachna,
Fredrick M. Wigley, Steven Morris, Allan C. Gelber, Antony Rosen, and
Livia Casciola-Rosen
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Muscle
Disease
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1885
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Differences in
Idiopathic Inflammatory Myopathy Phenotypes and Genotypes Between Mesoamerican
Mestizos and North American Caucasians: Ethnogeographic Influences in
the Genetics and Clinical Expression of Myositis
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Ejaz A. Shamim,
Lisa G. Rider, Janardan P. Pandey, Terrance P. O'Hanlon, Luis J. Jara,
Eduardo A. Samayoa, Ruben Burgos-Vargas, Janitzia Vazquez-Mellado, Jorge
Alcocer-Varela, Mario Salazar-Paramo, Abraham Garcia Kutzbach, James
D. Malley, Ira N. Targoff, Ignacio Garcia-De La Torre, and Frederick
W. Miller
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Vasculitis
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1894
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In Vitro Cytokine
Production and Proliferation of T Cells From Patients With Anti-Proteinase
3- and Antimyeloperoxidase-Associated Vasculitis, in Response to Proteinase
3 and Myeloperoxidase
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E. R. Popa, C. F.
M. Franssen, P. C. Limburg, M. G. Huitema, C. G. M. Kallenberg, and
J. W. Cohen Tervaert
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Amyloidosis
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1905
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A Pulse-Chase
Study Tracking the Conversion of Macrophage-Endocytosed Serum Amyloid
A Into Extracellular Amyloid
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Barbara Kluve-Beckerman,
John J. Manaloor, and Juris J. Liepnieks
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Diagnosis
and Clinical Features
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1914
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Discriminatory
Sonographic Criteria for the Diagnosis of Carpal Tunnel Syndrome
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S. M. Wong, J. F.
Griffith, A. C. F. Hui, A. Tang, and K. S. Wong
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1922
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Avascular Necrosis
of the Femoral Head in a Patient With Fabry's Disease: Identification
of Ceramide Trihexoside in the Bone by Delayed-Extraction Matrix-Assisted
Laser Desorption Ionization-Time-of-Flight Mass Spectrometry
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Hiroshi Horiuchi,
Naoto Saito, Seneki Kobayashi, Hiroyoshi Ota, Tamotsu Taketomi, and
Kunio Takaoka
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Animal
Models
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1926
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Kinetics of Bone
Protection by Recombinant Osteoprotegerin Therapy in Lewis Rats With
Adjuvant Arthritis
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Giuseppe Campagnuolo,
Brad Bolon, and Ulrich Feige
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1937
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Inhibition of
Adjuvant-Induced Arthritis by Interleukin-10-Driven Regulatory Cells
Induced Via Nasal Administration of a Peptide Analog of an Arthritis-Related
Heat-Shock Protein 60 T Cell Epitope
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Berent J. Prakken,
Sarah Roord, Peter J. S. van Kooten, Josee P. A. Wagenaar, Willem van
Eden, Salvatore Albani, and Marca H. M. Wauben
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1947
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Folate-Targeted
Imaging of Activated Macrophages in Rats With Adjuvant-Induced Arthritis
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Mary Jo Turk, Gert
J. Breur, William R. Widmer, Chrystal M. Paulos, Le-Cun Xu, Lee Ann
Grote, and Philip S. Low
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1956
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Effects of Long-Term
Estrogen Replacement Therapy on Osteoarthritis Severity in Cynomolgus
Monkeys
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Kimberley D. Ham,
Richard F. Loeser, Bruce R. Lindgren, and Cathy S. Carlson
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1964
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New Address,
Phone, and Fax Numbers for Arthritis & Rheumatism Editorial Office
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Concise
Communication
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1965
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Sustained Response
to Tumor Necrosis Factor [alpha]-Blocking Agents in Two Patients With
SAPHO Syndrome
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Annette D. Wagner,
Jan Andresen, Michael C. Jendro, Jan L. Hulsemann, and Henning Zeidler
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Clinical
Images
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1968
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Osteosclerotic
Myeloma Associated With the POEMS Syndrome
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James B. Chung and
Daniel A. Albert
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Letters
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1969
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High-Resolution
Ultrasound for the Study of Target Joints in Rheumatoid Arthritis
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Graciela S. Alarcon,
Robert Lopez-Ben, and Larry W. Moreland
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1970
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Reply
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Richard J. Wakefield,
Philip G. Conaghan, Philip O'Connor, Wayne W. Gibbon, Dennis McGonagle,
and Paul Emery
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1971
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Can Very High-Dose
Anti-Tumor Necrosis Factor Blockade at Onset of Rheumatoid Arthritis
Produce Long-Term Remission?
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Philip G. Conaghan,
Mark A. Quinn, Philip O'Connor, Richard J. Wakefield, Zunaid Karim,
and Paul Emery
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1973
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Reply
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Ravinder N. Maini
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1973
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Morbidity Not
Increased in Rheumatoid Arthritis Patient With Profound Lymphopenia
Following CD4 Monoclonal Antibody Therapy: Comment on the Article by
Isaacs et al
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Yamini Menon, Ranju
Singh, Raquel Cuchacovich, and Luis R. Espinoza
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1974
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Reply
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John D. Isaacs,
Herman Waldmann, Geoff Hale, and Brian L. Hazleman
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1974
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DNASE I Mutation
and Systemic Lupus Erythematosus in a Spanish Population: Comment on
the Article by Tew et al
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Eva Balada, Josep
Ordi-Ros, Susana Hernanz, Julieta Villarreal, Fina Cortes, Miquel Vilardell-Tarres,
and Moises Labrador
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1976
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Reply
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Monty B. Tew, Randall
W. Johnson, John D. Reveille, and Filemon K. Tan
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1977
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Call For a Trial
of Lyprinol, An Over-The-Counter 5-Lipoxygenase Inhibitor: Comment on
the Article by Kowal-Bielecka et al
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Michael W. Whitehouse
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1978
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Reply
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Oliver Distler,
Otylia Kowal-Bielecka, and Steffen Gay
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1978
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Congenital Fascial
Dystrophy, a New Scleroderma-Like Genetic Disease With Limitation of
Joint Mobility: Comment on the Clinical Image Presented by Di Rocco
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Stefania Jablonska
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1980
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Cognitive Function
in Fibromyalgia: Comment on the Article by Park et al
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A. S. Russell and
Roger Gervais
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1980
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Reply
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Denise C. Park,
Jennifer Glass, and Leslie Crofford
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25A
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ACR
Announcements
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Cover image: The
figure on the cover (from Turk et al, page 1949) illustrates gamma camera
imaging of hind limbs of arthritic rats injected with folic acid conjugated
with a 99mTc chelator. This scintigraphic approach, which detects cells
with high-affinity folate receptors, measures macrophages and could
be useful in assessing inflammation in diseases such as rheumatoid arthritis.
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