2143

Review: Cellular Mechanisms and the Role of Cytokines in Bone Erosions in Rheumatoid Arthritis

Ellen M. Gravallese and Steven R. Goldring

2152

Acidic Fibroblast Growth Factor in Synovial Cells

J. W. Thomas, T.-H. Thieu, V. M. Byrd, and Geraldine G. Miller

2160

Antigen-Presenting Cells Containing Bacterial Peptidoglycan in Synovial Tissues of Rheumatoid Arthritis Patients Coexpress Costimulatory Molecules and Cytokines

Ingrid A. Schrijver, Marie-Jose Melief, Paul P. Tak, Maarten P. Hazenberg, and Jon D. Laman

2169

The Mechanism of Taurine Chloramine Inhibition of Cytokine (Interleukin-6, Interleukin-8) Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Ewa Kontny, Katarzyna Szczepanska, Jacek Kowalczewski, Mariola Kurowska, Iwona Janicka, Janusz Marcinkiewicz, and W|flodzimierz Maslinski

2178

Decreased Cellular Activity and Replicative Capacity of Osteoblastic Cells Isolated from the Periarticular Bone of Rheumatoid Arthritis Patients Compared with Osteoarthritis Patients

Kazuo Yudoh, Hiroaki Matsuno, Ryusuke Osada, Fujio Nakazawa, Rie Katayama, and Tomoatsu Kimura

2189

Immortalized Human Adult Articular Chondrocytes Maintain Cartilage-Specific Phenotype and Responses to Interleukin-1[beta]

James R. Robbins, Beatrice Thomas, Lujian Tan, Bob Choy, Jack L. Arbiser, Francis Berenbaum, and Mary B. Goldring

2202

The Increased Swelling and Instantaneous Deformation of Osteoarthritic Cartilage is Highly Correlated with Collagen Degradation

Ruud A. Bank, Michael Soudry, Alice Maroudas, Joseph Mizrahi, and Johan M. TeKoppele

2211

Calcium Pentosan Polysulfate Inhibits the Catabolism of Aggrecan in Articular Cartilage Explant Cultures

Shannon E. Munteanu, Mirna Z. Ilic, and Christopher J. Handley

2219

CCAAT Binding Transcription Factor Binds and Regulates Human COL1A1 Promoter Activity in Human Dermal Fibroblasts: Demonstration of Increased Binding in Systemic Sclerosis Fibroblasts

Biagio Saitta, Svetlana Gaidarova, Lucia Cicchillitti, and Sergio A. Jimenez

2230

Role of Apoptosis and Transforming Growth Factor [beta]1 in Fibroblast Selection and Activation in Systemic Sclerosis

Ante Jelaska and Joseph H. Korn

2240

Increased Phosphorylation of Transcription Factor Sp1 in Scleroderma Fibroblasts: Association with Increased Expression of the Type I Collagen Gene

Hironobu Ihn and Kunihiko Tamaki

2248

Intercellular Adhesion Molecule 1 and [beta]2 Integrins in C1q-Stimulated Superoxide Production by Human Neutrophils: An Example of a General Regulatory Mechanism Governing Acute Inflammation

Shivraj Tyagi, Anne Nicholson-Weller, Sergei F. Barbashov, Sander W. Tas, and Lloyd B. Klickstein

2260

Acetylcholine Prevents Intercellular Adhesion Molecule 1 (CD54)-Induced Focal Adhesion Complex Assembly in Endothelial Cells Via a Nitric Oxide-cGMP-Dependent Pathway

Robert M. Clancy and Steven B. Abramson

2265

Clearance of Anti-Double-Stranded DNA Antibodies: The Natural Immune Complex Clearance Mechanism

Maria L. Craig, Alexander J. Bankovich, Jennifer L. McElhenny, and Ronald P. Taylor

2276

Role of Macrophages in Staphylococcus Aureus-Induced Arthritis and Sepsis

Margareta Verdrengh and Andrej Tarkowski

2283

The Major Role of Macrophages and Their Product Tumor Necrosis Factor [alpha] in the Induction of Arthritis Triggered by Bacterial DNA Containing CpG Motifs

Guo-Min Deng, Margareta Verdrengh, Zai-Qing Liu, and Andrej Tarkowski

2290

Development of Spontaneous Arthritis in [beta]2-Microglobulin-Deficient Mice without Expression of HLA-B27: Association with Deficiency of Endogenous Major Histocompatibility Complex Class I Expression

Daniel J. Kingsbury, John P. Mear, David P. Witte, Joel D. Taurog, Derry C. Roopenian, and Robert A. Colbert

2297

Evidence for Antimuscarinic Acetylcholine Receptor Antibody-Mediated Secretory Dysfunction in NOD Mice

Kim H.-T. Nguyen, Jason Brayer, Seunghee Cha, Stephanie Diggs, Utako Yasunari, George Hilal, Ammon B. Peck, and Michael G. Humphreys-Beher

2307

Nucleosomes are Major T and B Cell Autoantigens in Systemic Lupus Erythematosus

Anne Bruns, Stefan Bla\S, Gert Hausdorf, Gerd R. Burmester, and Falk Hiepe

2316

A Cost-Effectiveness Analysis of Treatment Options for Patients with Methotrexate-Resistant Rheumatoid Arthritis

Hyon K. Choi, John D. Seeger, and Karen M. Kuntz

2328

Fc[gamma] Receptor Type IIIA is Associated with Rheumatoid Arthritis in Two Distinct Ethnic Groups

Ann W. Morgan, Bridget Griffiths, Frederique Ponchel, Bridget M. N. Montague, Manir Ali, Philip P. Gardner, Hock-Chye Gooi, R. Deva Situnayake, Alexander F. Markham, Paul Emery, and John D. Isaacs

2335

Juvenile Rheumatoid Arthritis: Linkage to HLA Demonstrated by Allele Sharing in Affected Sibpairs

Sampath Prahalad, Mary H. Ryan, Edith S. Shear, Susan D. Thompson, Edward H. Giannini, and David N. Glass

2339

Efficacy and Safety of Diacerein in Osteoarthritis of the Knee: A Double-Blind, Placebo-Controlled Trial

Jean-Pierre Pelletier, Michael Yaron, Boulos Haraoui, Patrick Cohen, Menahem A. Nahir, Denis Choquette, Irina Wigler, Itzhak A. Rosner, Andre D. Beaulieu, and the Diacerein Study Group

2349

The 4G/5G Polymorphism of the Type 1 Plasminogen Activator Inhibitor Gene and Thrombosis in Patients with Antiphospholipid Syndrome

Dolors Tassies, Gerard Espinosa, Francisco Jose Munoz-Rodriguez, Carolina Freire, Ricard Cervera, Joan Monteagudo, Santiago Maragall, Gines Escolar, Miguel Ingelmo, Antoni Ordinas, Josep Font, and Joan Carles Reverter

2359

Muscle Abnormalities in Juvenile Dermatomyositis Patients: P-31 Magnetic Resonance Spectroscopy Studies

Jane H. Park, Kenneth J. Niermann, Nova M. Ryder, Amanda E. Nelson, Amrita Das, Alexander R. Lawton, Marta Hernanz-Schulman, and Nancy J. Olsen

2368

TNF[alpha]-308A Allele in Juvenile Dermatomyositis: Association with Increased Production of Tumor Necrosis Factor [alpha], Disease Duration, and Pathologic Calcifications

Lauren M. Pachman, Margaret R. Liotta-Davis, David K. Hong, T. Randall Kinsella, Eduardo P. Mendez, Jennifer M. Kinder, and Edwin H. Chen

2378

HLA-B44031;DRB1*1503 and Other Sub-Saharan African Major Histocompatibility Complex Haplotypes in African Americans and Afro-Caribbeans Carry C4A Gene Deletions: Implications for Ethnicity-Specific Lupus Susceptibility Genes

Patricia A. Fraser, Ling-Ying Lu, Wei-Zi Ding, Shakuntala N. Najundaswamy, Dong-Feng Chen, Gabriel Uko, and Susan Tonks

2379

Error in Reference in Article by Reinhold-Keller et al (Arthritis Rheum, May 2000) and in Authors' Institutional Affiliations in Article by McDermott et al (Arthritis Rheum, September 2000)

2380

Adoption by Lupus Patients Who are Infertile: Comment on the Article by Guballa et al

Leonard H. Sigal

2380

Nerissa Guballa, Sergio Schwartzman, Lisa R. Sammaritano, and Michael D. Lockshin

27A

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