2619

The Pathogenesis and Prevention of Joint Damage in Rheumatoid Arthritis: Advances from Synovial Biopsy and Tissue Analysis

Paul Peter Tak and Barry Bresnihan

2633

Amyloidosis of the Wrist and Multiple Myeloma

Jacques Labaye, Christian Duvic, and Georges N|fed|felec

2634

Retrotransposable L1 Elements Expressed in Rheumatoid Arthritis Synovial Tissue: Association with Genomic DNA Hypomethylation and Influence on Gene Expression

Michel Neidhart, Janine Rethage, Stefan Kuchen, Peter Kunzler, Robert M. Crowl, Mike E. Billingham, Renate E. Gay, and Steffen Gay

2648

Combination Benefit of Treatment with the Cytokine Inhibitors Interleukin-1 Receptor Antagonist and PEGylated Soluble Tumor Necrosis Factor Receptor Type I in Animal Models of Rheumatoid Arthritis

Alison M. Bendele, Elizabeth S. Chlipala, Jon Scherrer, Janet Frazier, Gina Sennello, William J. Rich, and Carl K. Edwards, III

2660

Regulatory Effects of Interleukin-4 and Interleukin-10 on Human Neutrophil Function Ex Vivo and on Neutrophil Influx in a Rat Model of Arthritis

Loretta A. Bober, Alberto Rojas-Triana, James V. Jackson, Michael W. Leach, Denise Manfra,Satwant K. Narula, and Michael J. Grace

2668

Amelioration of Collagen-Induced Arthritis in DBA/1J Mice by Recombinant TSG-6, a Tumor Necrosis Factor/Interleukin-1-Inducible Protein

C. Mindrescu, G. J. Thorbecke, M. J. Klein, J. Vilcek, and H.-G. Wisniewski

2678

Influence of Interferon-[gamma] Administration on the Severity of Experimental Group B Streptococcal Arthritis

Manuela Puliti, Christina Von Hunolstein, Francesco Bistoni, Paolo Mosci, Graziella Orefici, and Luciana Tissi

2687

The Genetic Ablation of Cyclooxygenase 2 Prevents the Development of Autoimmune Arthritis

Linda K. Myers, Andrew H. Kang, Arnold E. Postlethwaite, Edward F. Rosloniec, Scott G. Morham, Boris V. Shlopov, Sarita Goorha, and Leslie R. Ballou

2694

Treatment of Adjuvant-Induced Arthritis by Oral Administration of Mycobacterial Hsp65 During Disease

Pieter M. Cobelens, Cobi J. Heijnen, Edward E. S. Nieuwenhuis, Peter P. G. Kramer, Ruurd van der Zee, Willem van Eden, and Annemieke Kavelaars

2703

Expression of Cartilage Intermediate-Layer Protein/Nucleotide Pyrophosphohydrolase Parallels the Production of Extracellular Inorganic Pyrophosphate in Response to Growth Factors and with Aging

Jun Hirose, Ikuko Masuda, and Lawrence M. Ryan

2712

Analysis of Accumulated T Cell Clonotypes in Patients with Systemic Lupus Erythematosus

Tomohiro Kato, Manae Kurokawa, Hiroko Sasakawa, Kayo Masuko-Hongo, Toshihiro Matsui, Taichi Sekine, Chie Tanaka, Kazuhiko Yamamoto, and Kusuki Nishioka

2722

Restricted VH3 Gene Usage in Phage-Displayed Fab That are Selected by Intravenous Immunoglobulin

Awuku Osei, Martina M. Uttenreuther-Fischer, Heike Lerch, Gerhard Gaedicke, and Peter Fischer

2733

Diversity and Plasticity of the Anti-DNA Topoisomerase I Autoantibody Response in Scleroderma

Patricia A. Henry, Sergei P. Atamas, Vladimir V. Yurovsky, Irina Luzina, Fredrick M. Wigley, and Barbara White

2743

Relative Contributions of the Components of the American College of Rheumatology 20% Criteria for Improvement to Responder Status in Patients with Early Seropositive Rheumatoid Arthritis

Harold E. Paulus, Ken J. Bulpitt, Brian Ramos, Grace Park, and Weng Kee Wong, for the Western Consortium of Practicing Rheumatologists

2751

A Reappraisal of HAQ Disability in Rheumatoid Arthritis

Frederick Wolfe

2762

The Value of Sonography in the Detection of Bone Erosions in Patients with Rheumatoid Arthritis: A Comparison with Conventional Radiography

Richard J. Wakefield, Wayne W. Gibbon, Philip G. Conaghan, Philip O'Connor, Dennis McGonagle, Colin Pease, Michael J. Green, Douglas J. Veale, John D. Isaacs, and Paul Emery

2771

Linkage of Rheumatoid Arthritis to Insulin-Dependent Diabetes Mellitus Loci: Evidence Supporting a Hypothesis for the Existence of Common Autoimmune Susceptibility Loci

Anne Myerscough, Sally John, Jennifer H. Barrett, William E. R. Ollier, and Jane Worthington

2776

Reduced Bone Mineral Density in Male Rheumatoid Arthritis Patients: Frequencies and Associations with Demographic and Disease Variables in Ninety-Four Patients in the Oslo County Rheumatoid Arthritis Register

Glenn Haugeberg, Till Uhlig, Jan A. Falch, Johan I. Halse, and Tore K. Kvien

2785

The Inheritance of Hip Osteoarthritis in Iceland

Thorvaldur Ingvarsson, Stef|fan Einar Stef|fansson, Ingileif B. Hallgr|f8msd|fottir, Michael L. Frigge, Halld|for J|fonsson, Jr., Jeff Gulcher, Helgi J|fonsson, Jon Ingvar Ragnarsson, L. Stefan Lohmander, and K|fari Stef|fansson

2793

Fc[gamma] Receptor Polymorphisms in Systemic Lupus Erythematosus: Association with Disease and In Vivo Clearance of Immune Complexes

Hilde M. Dijstelbloem, Marc Bijl, Rob Fijnheer, Ronald H. M. Scheepers, Wia W. Oost, Marc D. Jansen, Wim J. Sluiter, Pieter C. Limburg, Ronald H. W. M. Derksen, Jan G. J. van de Winkel, and Cees G. M. Kallenberg

2801

Hepatitis C Virus Infection Mimicking Systemic Lupus Erythematosus: Study of Hepatitis C Virus Infection in a Series of 134 Spanish Patients with Systemic Lupus Erythematosus

Manuel Ramos-Casals, Josep Font, Mario Garc|f8a-Carrasco, Ricard Cervera, Sonia Jim|fenez, Olga Trejo, Gloria de la Red, Jose Ma S|fanchez-Tapias, and Miguel Ingelmo

2807

Differential Expression of Matrix Metalloproteinases in Labial Salivary Glands of Patients with Primary Sj|f-gren's Syndrome: Mechanisms of Exocrine Parenchyma Destruction

Paola P|ferez, Eduardo Goicovich, Cecilia Alliende, Sergio Aguilera, Cecilia Leyton, Claudio Molina, Rodrigo Pinto, Rafael Romo, Benjamin Martinez, and Mar|f8a-Julieta Gonz|falez

2818

Increased Risk of Developing Ankylosing Spondylitis Among First-Born Children

P. Baudoin, I. E. van der Horst-Bruinsma, A. J. Dekker-Saeys, S. Weinreich, P. D. Bezemer, and B. A. C. Dijkmans

2823

Regional Cerebral Blood Flow in Fibromyalgia: Single-Photon-Emission Computed Tomography Evidence of Reduction in the Pontine Tegmentum and Thalami

Richard Kwiatek, Leighton Barnden, Raymond Tedman, Richard Jarrett, Jenni Chew, Christopher Rowe, and Kevin Pile

2834

Analysis of the Antigen-Specific T Cell Response in Reactive Arthritis by Flow Cytometry

Andreas Thiel, Peihua Wu, Roland Lauster, Jurgen Braun, Andreas Radbruch, and Joachim Sieper

2843

Chronic Destructive Oligoarthritis Associated with Propionibacterium acnes in a Female Patient with Acne Vulgaris: Septic-Reactive Arthritis?

Leocadie Grassin Delyle, Olivier Vittecoq, Alain Bourdel, Fabrice Duparc, Chantal Michot, and Xavier Le Lo|f5t

2848

Brodie's Abscess with a Fistulous Tract Connecting with the Joint Space

M. A. Contreras, J. L. Andreu, J. Mulero, and C. Gonz|falez

2851

Lack of Association Between Mannose-Binding Lectin Gene Polymorphisms and Primary Sj|f-gren's Syndrome

Charles G. Mullighan, Sue Heatley, Peter G. Bardy, Sue Lester, Maureen Rischmueller, and Tom P. Gordon

2853

Potential Side Effects of Treatment with Glucosamine and Chondroitin

Theresa Danao-Camara

2853

Cystitis, Bladder Cancer, and Myelodysplasia in Patients with Wegener's Granulomatosis: Comment on the Article by Reinhold-Keller et al

Michael C. Sneller

2854

Eva Reinhold-Keller, Kirsten de Groot, and Wolfgang L. Gross

2855

False-Positive Results Obtained Using the Mantoux Test in Beh|fcet's Syndrome: Comment on the Article by Garc|f8a-Porr|fua et al

Matthew C. Pickering and Dorian O. Haskard

2855

Miguel A. Gonzalez-Gay and Carlos Garc|f8a-Porr|fua

2856

Hip Joint Remodeling in Systemic-Onset Juvenile Rheumatoid Arthritis

Sharon Banks and Barbara E. Ostrov

2857

Late-Breaking Abstracts and Second-Year Fellow Abstracts, American College of Rheumatology 2000 Annual Scientific Meeting

2865

Reviewers

2870

Contents, Volume 43, 2000

2902

Indexes

18A

ACR Announcements