Appendix C: Proposed One-Hour Neuropsychological Battery for SLE
Cognitive Tests:
North American Adult Reading Test (to estimate IQ)
Digit Symbol Substitution Test
Trail Making Test (Parts A & B)
Stroop Color and Word Test
California Verbal Learning Test
Rey-Osterrieth Complex Figure Test (with delayed recall)
WAIS III Letter-Number Sequencing
Controlled Oral Word Association Test (FAS)
Animal Naming
Finger Tapping
Additional Tests:
re: depressive
symptoms: Center for Epidemiological Studies-Depression Scale
(CES-D) (Reference 33)
re: fatigue and pain: Pain Visual Analog Scales, Fatigue Severity Scale (Reference 36)
re: self-reported
cognitive function: (e.g.) Cognitive Failures Questionnaire (CFQ)
Multiple Assessment Questionnaire (MAQ)
Patient Assessment of Own Functioning (PAOFI)
re: impact on daily living: (e.g.) SF-36 (Reference 37)
NB:
- Above battery is composed of tests that have individually been part of batteries and overlap to a large degree with brief batteries used in SLE patients and other medical populations.
- Identification of impairments on individual tests is based on existing normative data appropriate for age, education, sex, and ethnic group (wherever possible). The designation of impairment on the overall battery cannot be made without reference to an appropriate control group (not yet available).
- Clinical significance of changes in test scores over time must be defined in reference to normative data.
- The brief battery for SLE should be validated against a comprehensive battery that reliably identifies deficits in SLE patients compared with normal controls and, where appropriate for particular questions, other medical control groups.
