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Volume 40, No. 7, July 1997

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Official Journal of the American College of Rheumatology

Special Article

Review: Vasculitis in the Central Nervous System

Leonard H. Calabreese, George F. Duna, and J. T. Lie 1189

Clinical Science

Preliminary Definition of Improvement in Juvenile Arthritis

Edward H. Giannini, Nicolino Ruperto, Angelo Ravelli, Daniel J. Lovell, David T. Felson, and Alberto Martini 1202

T Cell Responses to Human Type II Collagen in Patients with Rheumatoid Arthritis and Healthy Controls

Neil Snowden, Irena Reynolds, Keith Morgan, and Lennox Holt 1210

Mycoplasma Infection and Rheumatoid Arthritis: Analysis of Their Relationship Using Immunoblotting and an Ultrasensitive Polymerase Chain Reaction Detection Method

Robert W. Hoffman, Frank X. O'Sullivan, Kim R. Schafermeyer, Terry L. Moore, Deborah Roussell, Robyn Watson-McKown, Mary F. Kim, and Kim S. Wise 1219

Fibrosing Alveolitis in Systemic Sclerosis: Indices of Lung Function in Relation to Extent of Disease on Computed Tomography

A. U. Wells, D. M. Hansell, M. B. Rubens, A. D. King, D. Cramer, C. M. Black, and R. M. du Bois 1229

Scleroderma Lung Fibroblasts Exhibit Elevated and Dysregulated Type I Collagen Biosynthesis

Xu Shi-Wen, Christopher P. Denton, Alan McWhirter, George Bou-Gharios, David J. Abraham, Roland M. du Bois, and Carol M. Black 1237

Pregnancy in Relapsing Polychondritis: Twenty-Five Pregnancies in Eleven Patients

Thomas Papo, Bertrand Wechsler, Olivier Bletry, Anne-Marie Piette, Pierre Godeau, and Jean-Charles Piette 1245

Usefulness of Procalcitonin for Differentiation Between Activity of Systemic Autoimmune Disease (Systemic Lupus Erythematosus/Systemic Antineutrophil Cytoplasmic Antibody-Associated Vasculitis) and Invasive Bacterial Infection

O. K. Eberhard, M. Haubitz, F. M. Brunkhorst, V. Kliem, K. M. Koch, and R. Brunkhorst 1250

Clinical, Serologic, and Immunogenetic Features in Polish Patients with Idiopathic Inflammatory Myopathies

Irena Hausmanowa-Petrusewicz, Elzbieta Kowalska-Oledzka, Frederick W. Miller, Maria Jarzabek-Chorzelska, Ira N. Targoff, Maria Blaszczyk-Kostanecka, and Stefania Jablonska 1257

The AIMS2-SF: A Short Form of the Arthritis Impact Measurement Scales 2

Francis Guillemin, Joel Coste, Jacques Pouchot, Marc Ghezail, Christian Bregeon, Jacques Sany, and The French Quality of Life in Rheumatology Group 1267

Basic Science

Differential Effects of Aging on Human Chondrocyte Responses to Transforming Growth Factor β: Increased Pyrophosphate Production and Decreased Cell Proliferation

Fred Rosen, Greg McCabe, Jacqueline Quach, Joell Solan, Robert Terkeltaub, J. Edwin Seegmiller, and Martin Lotz 1275

Alteration of Cartilage Metabolism by Cells from Osteoarthritic Bone

Carole I. Westacott, Ginette R. Webb, Mark G. Warnock, Jane V. Sims, and Christopher J. Elson 1282

Inhibition of Rheumatoid Synovial Fibroblast Proliferation by Antisense Oligonucleotides Targeting Proliferating Cell Nuclear Antigen Messenger RNA

Yoshitaka Morita, Naoki Kashihara, Masahiro Yamamura, Hideyuki Okamoto, Seishi Harada, Yohei Maeshima, Kazunori Okamoto, and Hirofumi Makino 1292

Interleukin-1β-Stimilated Invasion of Articular Cartilage by Rheumatoid Synovial Fibroblasts is Inhibited by Antibodies to Specific Integrin Receptors and by Collagenase Inhibitors

Allan Z. Wang, Jane C. Wang, Gregory W. Fisher, and Herbert S. Diamond 1298

Adenosine A Receptor Promotion of Multinucleated Giant Cell Formation by Human Monocytes: A Mechanism for Methotrexate-Induced Nodulosis in Rheumatoid Arthritis

Joan T. Merrill, Christine Shen, David Schreibman, Dan Coffey, Olga Zakharenko, Robert Fisher, Robert G. Lahita, Jane Salmon, and Bruce N. Cronstein 1308

Use of T Cell Reeptor/HLA-DRB1*04 Molecular Modeling to Predict Site-Specific Interactions for the DR Shared Epitope Associated with Rheumatoid Arthritis

Julie E. Penzotti, Gerald T. Nepom, and Terry P. Lybrand 1316

Involvement of Endogenous Kinins in the Pathogenesis of Peptidoglycan-Induced Arthritis in the Lewis Rat

Charles Blais, Jr., R‚jean Couture, Guy Drapeau, Robert W. Colman, and Albert Adam 1327

Mechanisms of Drug-Induced Lupus. III. Sex-Specific Differences in T Cell Homing May Explain Increased Disease Severity in Female Mice

Raymond Yung, Robert Williams, Kent Johnson, Carrie Phillips, Lloyd Stoolman, Sandra Chang, and Bruce Richardson 1334

Human Autoantibodies Stabilize the Quaternary Structure of Ku Antigen

Jingsong Wang, Xingwen Dong, Lovorka Stojanov, Donald Kimpel, Minoru Satoh, and Westley H. Reeves 1344

Clinical Images

Skin Hyperpigmentation Associated with Minocycline Therapy

Herbert Kaplan 1353

Case Report

Wegener's Granulomatosis in Pregnancy

Phot Luisiri, Nancy Joseph Lance, and James J. Curran 1354

Radiologic Vignette

Bone Pain in a Transplant Patient

John H. Stone, Charles G. Peterfy, and Kenneth E. Sack 1361

Concise Communication

Correlation of Serum IgG Antibodies to Recombinant P0 Fusiuon Protein with IgG Antibodies to Carboxyl-Terminal 22 Synthetic Peptides and Carobxyl-Terminal 22 Amino Acid-Deleted Recombinant P0 Fusion Protein in Patients with Systemic Lupus Erythematosus

Taku Yoshio, Jun-Ichi Masuyama, Seiji Minota, Masahiro Iwamoto, Akio Mimori, Akira Takeda, Hitoaki Okazaki, and Shogo Kano 1364

Letters

Antibodies to β2-Glycoprotein I in Patients with Systemic Lupus Erythematosus: Comment on the Articles by Tsutsumi et al and Roubey et al

Murat Inanc and David A. Isenberg 1366

Reply

Akito Tsutsumi, Eiji Matsuura, Kenji Ichikawa, and Takao Koike 1366

Reply

Robert A. S. Roubey and Michael A. Maldonado 1367

Tumor Necrosis Factor a Microsatellite Polymorphism in Rheumatoid Arthritis: Comment on the Article by Hajeer et al

A. Perdriger, G. ChalŠs, M. Alizadeh, and G. Semana 1368

Reply

Ali H. Hajeer, Jane Worthington, Alan J. Silman, and William E. R. Ollier 1370

Effects of Interferon á-1B in Rheumatoid Arthritis: A Case Report

Joseph A. Jabaily and J. Stephen Thompson 1370

ACR Announcements 15A