Arthritis Care & Research
Official Journal of the American College of Rheumatology
Volume 47, No. 1, February 2002
EDITORIALS
1 Need for Circumspection
in Prescribing Tumor Necrosis Factor Inhibitors and Other Biologic Response
Eric L. Matteson
5 Alternative Medicine
and The Arthritis Foundation
Donald M. Marcus
ORIGINAL ARTICLE
Ankylosing Spondylitis
8 Assessment of Fatigue
in Patients With Ankylosing Spondylitis: A Psychometric Analysis
Astrid van Tubergen,
Jolanda Coenen, Robert Landewe, Anneke Spoorenberg, Astrid Chorus, Annelies
Boonen, Sjef van der Linden, and Desiree van der Heijde
Etanercept Therapy
17 Experience With
Etanercept in an Academic Medical Center: Are Infection Rates Increased?
Kristine Phillips,
M. Elaine Husni, Elizabeth W. Karlson, and Jonathan S. Coblyn
Fibromyalgia
22 The Effects of
Progressive Strength Training and Aerobic Exercise on Muscle Strength
Daniel S. Rooks, Caroline
B. Silverman, and Fred G. Kantrowitz
Giant-Cell Arteritis
29 A Strong Initial
Systemic Inflammatory Response is Associated With Higher Corticosteroid
Requirements and Longer Duration of Therapy in Patients With Giant-Cell
Arteritis
Jose Hernandez-Rodriguez,
Ana Garcia-Martinez, Jordi Casademont, Xavier Filella, Maria-Jose Esteban,
Alfonso Lopez-Soto, Joaquim Fernandez-Sola, Alvaro Urbano-Marquez, Josep
M. Grau, and Maria C. Cid
Nonsteroidal Antiinflammatory
Drug Therapy
36 Role of Initial
NSAID Choice and Patient Risk Factors in the Prevention of NSAID Gastropathy:
A Decision Analysis
A. Mark Fendrick, Rajesh R. Bandekar, Michael E. Chernew, and James M. Scheiman
Osteoarthritis
44 Joint Protection
and Home Hand Exercises Improve Hand Function in Patients With Hand Osteoarthritis:
A Randomized Controlled Trial
Tanja Alexandra Stamm,
Klaus Peter Machold, Josef Sebastian Smolen, Sabine Fischer, Kurt Redlich,
Winfried Graninger, Wolfgang Ebner, and Ludwig Erlacher
50 Structural Effect
of Avocado/Soybean Unsaponifiables on Joint Space Loss in Osteoarthritis
of the Hip
Michel Lequesne, Emmanuel
Maheu, Christian Cadet, and Renee-Liliane Dreiser
Rheumatoid Arthritis
59 Step-Down Approach
Using Either Cyclosporin A or Methotrexate as Maintenance Therapy in Early
Rheumatoid Arthritis
Antonio Marchesoni,
Norma Battafarano, Marco Arreghini, Raffaele Pellerito, Maria Cagnoli,
Porziana Prudente, Alfonso Cerase, Francesco Priolo, and Sergio Tosi
67 The Number of Deformed
Joints as a Surrogate Measure of Damage in Rheumatoid Arthritis
Carlos H. Orces, Inmaculada
del Rincon, Michael P. Abel, and Agustin Escalante
Systemic Sclerosis
73 Design and Quality
Considerations for Randomized Controlled Trials in Systemic Sclerosis
Maria Kyriakidi and
John P. A. Ioannidis
CONTRIBUTIONS FROM THE FIELD
82 The Effect of Graded
Resistance Exercise on Fibromyalgia Symptoms and Muscle Bioenergetics:
A Pilot Study
Stanley E. Geel and
Robert A. Robergs
SPECIAL ARTICLES
87 Combination Cytokine
Therapy: The Next Generation of Rheumatoid Arthritis Therapy?
Arthur Kavanaugh
93 American College
of Rheumatology Basic Research Conference: Genetics and Genomics in Rheumatic
Disease
John B. Harley, Jeffrey
Trent, and Daniel L. Kastner, for the Conference Participants
REVIEW ARTICLE
99 Splinting the Juvenile
Arthritic Wrist: A Clinical Observation
Paul J. M. Helders,
Janjaap van der Net, and Marianne K. Nieuwenhuis
TRAINEE ROUNDS
104 Cryptococcal Arthritis,
Tendinitis, Tenosynovitis, and Carpal Tunnel Syndrome: Report of a Case
and Review of the Literature
Kimberly M. Bruno,
Ladan Farhoomand, Bonita S. Libman, Charles N. Pappas, and Frank J. Landry
LETTERS
109 Are You Better?
Comment on the Article by Beaton et al
Jeremy G. Jones
109 Vesalius, Also
a Rheumatologist?
Thierry Appelboom
and Joelle Margaux
ANNOUNCEMENTS
Cover Illustration:
Polyarteritis nodosa was the first noninfectious vasculitis to be described
and studied in detail. Research on this group of vasculitides has been
the cornerstone for understanding the pathophysiology of other forms of
idiopathic vasculitis. Historically, most forms of vasculitis described
subsequently have been characterized and classified on the basis of features
either similar to or distinct from polyarteritis.
In 1852, Karl (later
Freiherr von) Rokitansky, the great Viennese pathologist, described the
first case of polyarteritis nodosa (1). He had noted aneurysmal lesions
with nodes in numerous arteries observed at autopsy in a 23-year-old shoemaker's
journeyman, Wenzel Plohner. The drawing of the mesentery shows multiple
macroscopically apparent arterial nodules with aneurysms at the branching
point of smaller arteries. Rokitansky did not microscopically examine
the specimen, and did not recognize the inflammatory nature of the vascular
lesion. He viewed the aneurysms as located eccentrically on the sides
of the involved artery, connected to the lumen of the artery by a small
opening, or ostium. In describing the aneurysms, he states ``Larger or
smaller, often barely perceptible, needle-point sized openings in the
vessel lumen led into these, which had the appearance of a delicate vessel
ostium'' (2).
The classic description
of polyarteritis nodosa by the internist Adolf Kussmaul, and pathologist
Rudolf Maier in Freiburg, Germany, is based on their report of a 27-year-old
journeyman tailor by the name of Carl Seufarth (3). At autopsy, nodules
along medium-sized arteries were visible to the naked eye. The drawing
of the patient's heart demonstrates numerous nodular thickenings of the
coronary arteries. Histologic examination revealed ``abundant nucleosis''
with “alternating areas of constrictions and dilatations” (2).
1. Rokitansky K. eber
einige der wichtigsten Erkrankungen der Arterien. Denkschriften der kaiserlichen
Akademie der Wissenschaften (mathematisch-naturwissenschaftliche Classe).
Vienne, kaiserlich-koniglich Hof-und Staatsdruckerei. 1852;4:1-72.
2. Matteson EL. A
history of idiopathic vasculitis. Rochester (MN): Mayo Clinic Press; 1999.
3. Jussmaul A, Maier
R, Ueber eine bisher nicht beschriebene eigenthumliche Arterienerkrankung
(Periarteritis nodosa), die mit Morbus Brightii und rapid fortschreitender
allgemeiner Muskellahmung einhergeht. Deutsche Arch Klin Med 1866;1:484-516.(Submitted
by Eric L. Matteson, MD, MPH, Mayo Clinic, Rochester, MN)
