Abstract


Presentation Number: 116

Quantitative Ultrasonography in Patients with Carpal Tunnel Syndrome: Is it Time to Say Farewell to Nerve Conduction Studies?

Yasser M. A. El Miedany1, Sohair Adel Aty2, Samia Ashour3. 1Rheumatology and Rehab. Dept. Ain Shams University, Cairo, Egypt; 2Radiology Dept. Ain Shams University, Cairo, Egypt; 3Neuropsychiatry Dept. Ain Shams University, Cairo, Egypt

Objective: to assess the optimal discriminatory sonographic criteria and relevant threshold values in patients with carpal tunnel syndrome (CTS) and to evaluate quantitative ultrasonography (US) as a tool for diagnosis and treatment of patients suffering from carpal tunnel syndrome in comparison to electrophysiologic study.

Methods: Seventy-eight patients with CTS and 78 asymptomatic controls who were matched for age and sex were enrolled and underwent ultrasonography of the wrists. All patients and control group completed a self-administered questionnaire. An electrophysiologic testing was done for all patients. Data from the patient and the control groups were compared to determine the diagnostic relations in patients with CTS and grade of severity.

Results: There was a high degree of correlation between the conduction abnormalities of the median nerve as detected by electrodiagnostic tests, self administered assessment and the measurement of its cross sectional area (CSA) by US (p<0.05). Various levels of disease severity can also be illustrated by US giving confident results for diagnosis, treatment planning and following the patients with CTS. In 16 patients (17%) there was tenosynovitis/localised swelling in the tendons in the carpal tunnel as the primary cause of CTS. Cutoff point of 10 mm2 for the mean CSA of the median nerve was found to be the upper limit for normal values. In addition, our study revealed that 13.03 mm2 and 15.02 mm2 were the best cutoff points to discriminate between the mild and moderate groups; as well as between moderate and severe groups.

Conclusion: high frequency ultrasound examination of the median nerve and measurement of its cross sectional area should be strongly considered as a new, alternative diagnostic modality for the evaluation of CTS. It offers high diagnostic accuracy as indicated by high correlation to the present standard EMG as well as patient oriented measures. Moreover, ultrasound provides a reliable method for following response to therapy.

Disclosure: Y.M.A. El Miedany, None; S. Adel Aty, None; S. Ashour, None.


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