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Drug Induced Lupus Erythematosus

Drug-induced lupus erythematosus is an autoimmune disorder that is brought on by a reaction to medication. Specific criteria for diagnosing drug-induced lupus have not been formally established. However, some symptoms overlap with those of SLE. These include:

  • Muscle and joint pain and swelling
  • Flu-like symptoms of fatigue and fever
  • Serositis (inflammation around the lungs or heart that causes pain or discomfort)
  • Certain laboratory test abnormalities.

Once the suspected medication is stopped, symptoms should decline within days. Usually symptoms disappear within one or two weeks. Drug-induced lupus can be diagnosed with certainty only by resolution of symptoms and their failure to recur after stopping the medication.

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- Patient Care

  1. Obtain the appropriate history to determine if a patient might have drug induced lupus
  2. Recognize the possible symptoms of drug induced lupus
  3. Identify the drugs known to cause drug induced lupus
  4. Determine the appropriate serologies to help diagnose drug induced lupus
  5. Distinguish the appropriate medical management
  6. Determine the appropriate follow-up for the patient
  7. Recognize the differences between and diagnosis of drug induced lupus and idiopathic lupus and the implications for a patient

- Medical Knowledge

  1. Identify the drugs known to cause drug induced lupus
  2. Identify the treatment for drug induced lupus
  3. Recognize the symptoms and clinical findings of drug induced lupus

- Practice-based Learning and Improvement

  1. Demonstrate the ability to review and interpret the literature relevant to diagnosing drug induced lupus and possible causes
  2. Set learning goals in drug induced lupus diagnosis and management
  3. Effectively use laboratory testing results to manage patient care decisions and enhance education of the patient and the referring physician
  4. Develop a willingness to learn from errors and use errors in a constructive way to learn and to improve the systems for patient care
  5. Utilize web-based resources to enhance learning about drug induced lupus

- Interpersonal and Communication Skills

  1. Discuss the results of serologies that suggest a diagnosis of drug induced lupus
  2. Discuss the diagnosis of drug induced lupus with a patient
  3. Explain the possible treatment options of drug induced lupus based on symptoms
  4. Discuss the differences between a diagnosis of drug induced lupus and idiopathic lupus

- Professionalism

  1. Recognize the importance of patient confidentiality and privacy
  2. Understand the need to provide supportive care
  3. Encourage patients to ask questions regarding their disease and empower them to be participants in their care
  4. Provide adequate time and accessibility to address patient concerns
  5. Demonstrate an understanding of informed consent with regards to therapeutic options in the treatment of drug induced lupus

- Systems-based Practice

  1. Create a team approach to manage patients with drug induced lupus engaging physicians from multiple disciplines
  2. Identify barriers to access and delivery of care to patients with complex, multi-system diseases
  3. Understand the resources available to help with delivery of care and patient support
  4. Identify the ways in which one can be a patient advocate including obtaining prior authorization for medications, treatments and diagnostic tests
  5. Behave as a consultant to referring providers to enhance comprehensive care of patients in terms of lupus management
  6. Demonstrate the ability to collaborate with other health care providers in evaluating a patient
  7. Implement a cost-effective management plan for a patient with drug induced lupus