Glossary

Looking for rheumatic disease types, treatments, and associated rheumatology definitions? From abatacept to WOMAC, learn about common terms related to arthritis and rheumatic and musculoskeletal diseases. Looking for information about MACRA? See MACRA terms and definitions.


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Ibandronate (Boniva)

Oral and intravenous drug that is used for treating osteoporosis. It is a member of the bisphosphonate class of drugs. After menopause, there is an increased rate of bone loss leading to osteoporosis, and ibandronate has been shown to increase bone density and decrease fractures of bones.

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Imaging

Production of a clinical image using x-rays, ultrasound, computed tomography, magnetic resonance imaging, radionuclide scanning, and thermography.

Immunogenicity

State or property of being antigenic.

Immunology

Science concerned with the various phenomena of immunity, induced sensitivity, and allergy.

Infection

Invasion of the body with organisms that have the potential to cause disease.

Inflamed blood vessels

Another term for vasculitis, this is inflammation of arteries, veins, and capillaries. May occur in autoimmune diseases when the immune system attacks healthy tissues by mistake. Signs of blood vessel inflammation include pain, redness, swelling, heat sensation, and loss of function in the affected area. Can cause interruption of the blood supply to organs, causing damage. It can also lead to blood vessels bursting, known as an aneurysm.

Inflammation

Fundamental pathologic process consisting of a dynamic complex of cytologic and chemical reactions that occur in the affected blood vessels and adjacent tissues in response to an injury or abnormal stimulation caused by a physical, chemical, or biologic agent.

Inflammatory myopathies

Group of diseases that involve chronic muscle inflammation, accompanied by muscle weakness; includes polymyositis, dermatomyositis, and inclusion body myositis.

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Infliximab (Remicade)

Chimeric anti-tumor necrosis factor α (anti-TNFα) monoclonal antibody containing a murine TNFα binding region and a human IgG1 backbone; used to treat rheumatoid arthritis and other inflammatory diseases.

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Insulin growth factor (IGF)

Most important somatomedin for postnatal growth; produced in the liver, kidney, muscle, pituitary, gastrointestinal tract, and chondrocytes.

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