Glossary

Looking for rheumatic disease types, treatments, and associated rheumatology definitions? From abatacept to WOMAC, learn about common terms related to arthritis and rheumatic and musculoskeletal diseases. Looking for information about MACRA? See MACRA terms and definitions.


H

Hallux valgus

Deviation of the distal portion of the great toe, at the metatarsophalangeal joint, toward the outer or lateral side of the foot.

Health Assessment Questionnaire (HAQ)

Developed as a comprehensive measure of outcome in patients with a wide variety of rheumatic diseases, including rheumatoid arthritis, osteoarthritis, juvenile rheumatoid arthritis, lupus, scleroderma, ankylosing spondylitis, fibromyalgia, and psoriatic arthritis.

Health risk assessment

Method of describing an individual’s chance of falling ill or dying of a specific condition, based on actuarial calculations that compare chance of acquiring a condition with that of the general population expressed as the expected age at which death or disease will occur, and intended as a way of drawing an individual’s attention to the probable health consequences of risk behavior.

Health-related quality of life

Assessment of a person’s well-being with regard to physical health.

Hemodialysis

Dialysis of soluble substances and water from the blood by diffusion through a semipermeable membrane.

Hepatotoxicity

Capacity of a drug, chemical, or other exposure to produce injury to the liver.

Heritability

In genetics, statistical term used to denote the proportion of phenotypical variance due to variance in genotypes that is genetically determined, denoted by h2.

Hip arthroplasty/replacement

Operation to restore as far as possible the integrity and functional power of a hip joint.

Hormone replacement therapy

Administration of sex hormones to women after menopause or oophorectomy.

Human leukocyte antigen (HLA)

System designation for the gene products of at least four linked loci and a number of subloci on the sixth human chromosome that have been shown to have a strong influence on human allotransplantation.

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